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Bosutinib prevents vascular leakage by reducing focal adhesion turnover and reinforcing junctional integrity.

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Title: Bosutinib prevents vascular leakage by reducing focal adhesion turnover and reinforcing junctional integrity.
Authors: Botros L; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Pulmonology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands.; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Physiology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands., Pronk MCA; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Physiology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands., Juschten J; Amsterdam UMC, University of Amsterdam, Department of Intensive Care, 1105 AZ Amsterdam, The Netherlands., Liddle J; GlaxoSmithKline, Stevenage, Hertfordshire, SG1 2NY, UK., Morsing SKH; Molecular Cell Biology Lab at Dept. Molecular Cellular Haemostasis, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands., van Buul JD; Molecular Cell Biology Lab at Dept. Molecular Cellular Haemostasis, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands., Bates RH; GlaxoSmithKline, Stevenage, Hertfordshire, SG1 2NY, UK., Tuinman PR; Amsterdam UMC, University of Amsterdam, Department of Intensive Care, 1105 AZ Amsterdam, The Netherlands., van Bezu JSM; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Physiology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands., Huveneers S; Amsterdam UMC, University of Amsterdam, Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, 1105 AZ Amsterdam, The Netherlands., Bogaard HJ; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Pulmonology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands., van Hinsbergh VWM; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Physiology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands., Hordijk PL; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Physiology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands., Aman J; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Pulmonology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands j.aman@amsterdamumc.nl.
Source: Journal of cell science [J Cell Sci] 2020 May 14; Vol. 133 (9). Date of Electronic Publication: 2020 May 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-9137 (Electronic) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Bosutinib prevents vascular leakage by reducing focal adhesion turnover and reinforcing junctional integrity.
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  Data: <searchLink fieldCode="AU" term="%22Botros+L%22">Botros L</searchLink>; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Pulmonology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands.; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Physiology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pronk+MCA%22">Pronk MCA</searchLink>; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Physiology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Juschten+J%22">Juschten J</searchLink>; Amsterdam UMC, University of Amsterdam, Department of Intensive Care, 1105 AZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Liddle+J%22">Liddle J</searchLink>; GlaxoSmithKline, Stevenage, Hertfordshire, SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Morsing+SKH%22">Morsing SKH</searchLink>; Molecular Cell Biology Lab at Dept. Molecular Cellular Haemostasis, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Buul+JD%22">van Buul JD</searchLink>; Molecular Cell Biology Lab at Dept. Molecular Cellular Haemostasis, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bates+RH%22">Bates RH</searchLink>; GlaxoSmithKline, Stevenage, Hertfordshire, SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Tuinman+PR%22">Tuinman PR</searchLink>; Amsterdam UMC, University of Amsterdam, Department of Intensive Care, 1105 AZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Bezu+JSM%22">van Bezu JSM</searchLink>; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Physiology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Huveneers+S%22">Huveneers S</searchLink>; Amsterdam UMC, University of Amsterdam, Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, 1105 AZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bogaard+HJ%22">Bogaard HJ</searchLink>; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Pulmonology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Hinsbergh+VWM%22">van Hinsbergh VWM</searchLink>; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Physiology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hordijk+PL%22">Hordijk PL</searchLink>; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Physiology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Aman+J%22">Aman J</searchLink>; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Pulmonology, Amsterdam Cardiovascular Sciences, 1081 BT Amsterdam, The Netherlands j.aman@amsterdamumc.nl.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Company+of+Biologists%22">Company of Biologists </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0052457 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-9137 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219533%22">00219533 </searchLink><i>NLM ISO Abbreviation: </i>J Cell Sci <i>Subsets: </i>MEDLINE
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              Text: 2020 May 14
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