Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition.
Saved in:
| Title: | Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition. |
|---|---|
| Authors: | Mondal G; Department of Pathology, University of California, San Francisco, CA, USA., Lee JC; Department of Pathology, University of California, San Francisco, CA, USA., Ravindranathan A; Department of Pathology, University of California, San Francisco, CA, USA., Villanueva-Meyer JE; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA., Tran QT; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA., Allen SJ; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA., Barreto J; Department of Pathology, University of California, San Francisco, CA, USA., Gupta R; Department of Pathology, University of California, San Francisco, CA, USA., Doo P; Institute for Human Genetics, University of California, San Francisco, CA, USA., Van Ziffle J; Department of Pathology, University of California, San Francisco, CA, USA.; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA., Onodera C; Department of Pathology, University of California, San Francisco, CA, USA.; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA., Devine P; Department of Pathology, University of California, San Francisco, CA, USA.; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA., Grenert JP; Department of Pathology, University of California, San Francisco, CA, USA.; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA., Samuel D; Department of Hematology/Oncology, Valley Children's Hospital, Madera, CA, USA., Li R; Department of Pathology, Children's of Alabama, Birmingham, AL, USA., Metrock LK; Department of Pediatric Hematology/Oncology, University of Alabama, Birmingham, AL, USA., Jin LW; Department of Pathology, University of California Davis Medical Center, Sacramento, CA, USA., Antony R; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California Davis Medical Center, Sacramento, CA, USA., Alashari M; Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA., Cheshier S; Department of Neurosurgery, University of Utah School of Medicine, Salt Lake City, UT, USA., Whipple NS; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA., Bruggers C; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA., Raffel C; Department of Neurological Surgery, University of California, San Francisco, CA, USA., Gupta N; Department of Neurological Surgery, University of California, San Francisco, CA, USA., Kline CN; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, CA, USA.; Department of Neurology, University of California, San Francisco, CA, USA., Reddy A; Department of Neurology, University of California, San Francisco, CA, USA., Banerjee A; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, CA, USA., Hall MD; Department of Radiation Oncology, Miami Cancer Institute, Miami, FL, USA., Mehta MP; Department of Radiation Oncology, Miami Cancer Institute, Miami, FL, USA., Khatib Z; Division of Hematology/Oncology, Department of Pediatrics, Nicklaus Children's Hospital, Miami, FL, USA., Maher OM; Division of Hematology/Oncology, Department of Pediatrics, Nicklaus Children's Hospital, Miami, FL, USA., Brathwaite C; Department of Pathology, Nicklaus Children's Hospital, Miami, FL, USA., Pekmezci M; Department of Pathology, University of California, San Francisco, CA, USA., Phillips JJ; Department of Pathology, University of California, San Francisco, CA, USA.; Department of Neurological Surgery, University of California, San Francisco, CA, USA., Bollen AW; Department of Pathology, University of California, San Francisco, CA, USA., Tihan T; Department of Pathology, University of California, San Francisco, CA, USA., Lucas JT Jr; Department of Radiation Oncology, St Jude Children's Research Hospital, Memphis, TN, USA., Broniscer A; Division of Pediatric Hematology/Oncology, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Berger MS; Department of Neurological Surgery, University of California, San Francisco, CA, USA., Perry A; Department of Pathology, University of California, San Francisco, CA, USA.; Department of Neurological Surgery, University of California, San Francisco, CA, USA., Orr BA; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA., Solomon DA; Department of Pathology, University of California, San Francisco, CA, USA. david.solomon@ucsf.edu.; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA. david.solomon@ucsf.edu. |
| Source: | Acta neuropathologica [Acta Neuropathol] 2020 Jun; Vol. 139 (6), pp. 1071-1088. Date of Electronic Publication: 2020 Apr 17. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| FullText | Links: – Type: pdflink Text: Availability: 1 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 32303840 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Mondal+G%22">Mondal G</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lee+JC%22">Lee JC</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ravindranathan+A%22">Ravindranathan A</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Villanueva-Meyer+JE%22">Villanueva-Meyer JE</searchLink>; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tran+QT%22">Tran QT</searchLink>; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Allen+SJ%22">Allen SJ</searchLink>; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Barreto+J%22">Barreto J</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gupta+R%22">Gupta R</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Doo+P%22">Doo P</searchLink>; Institute for Human Genetics, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Van+Ziffle+J%22">Van Ziffle J</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Onodera+C%22">Onodera C</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Devine+P%22">Devine P</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Grenert+JP%22">Grenert JP</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Samuel+D%22">Samuel D</searchLink>; Department of Hematology/Oncology, Valley Children's Hospital, Madera, CA, USA.<br /><searchLink fieldCode="AU" term="%22Li+R%22">Li R</searchLink>; Department of Pathology, Children's of Alabama, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Metrock+LK%22">Metrock LK</searchLink>; Department of Pediatric Hematology/Oncology, University of Alabama, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Jin+LW%22">Jin LW</searchLink>; Department of Pathology, University of California Davis Medical Center, Sacramento, CA, USA.<br /><searchLink fieldCode="AU" term="%22Antony+R%22">Antony R</searchLink>; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California Davis Medical Center, Sacramento, CA, USA.<br /><searchLink fieldCode="AU" term="%22Alashari+M%22">Alashari M</searchLink>; Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Cheshier+S%22">Cheshier S</searchLink>; Department of Neurosurgery, University of Utah School of Medicine, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Whipple+NS%22">Whipple NS</searchLink>; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Bruggers+C%22">Bruggers C</searchLink>; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Raffel+C%22">Raffel C</searchLink>; Department of Neurological Surgery, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gupta+N%22">Gupta N</searchLink>; Department of Neurological Surgery, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kline+CN%22">Kline CN</searchLink>; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, CA, USA.; Department of Neurology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Reddy+A%22">Reddy A</searchLink>; Department of Neurology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Banerjee+A%22">Banerjee A</searchLink>; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hall+MD%22">Hall MD</searchLink>; Department of Radiation Oncology, Miami Cancer Institute, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Mehta+MP%22">Mehta MP</searchLink>; Department of Radiation Oncology, Miami Cancer Institute, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Khatib+Z%22">Khatib Z</searchLink>; Division of Hematology/Oncology, Department of Pediatrics, Nicklaus Children's Hospital, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Maher+OM%22">Maher OM</searchLink>; Division of Hematology/Oncology, Department of Pediatrics, Nicklaus Children's Hospital, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Brathwaite+C%22">Brathwaite C</searchLink>; Department of Pathology, Nicklaus Children's Hospital, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Pekmezci+M%22">Pekmezci M</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Phillips+JJ%22">Phillips JJ</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.; Department of Neurological Surgery, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bollen+AW%22">Bollen AW</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tihan+T%22">Tihan T</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lucas+JT+Jr%22">Lucas JT Jr</searchLink>; Department of Radiation Oncology, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Broniscer+A%22">Broniscer A</searchLink>; Division of Pediatric Hematology/Oncology, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Berger+MS%22">Berger MS</searchLink>; Department of Neurological Surgery, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Perry+A%22">Perry A</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA.; Department of Neurological Surgery, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Orr+BA%22">Orr BA</searchLink>; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Solomon+DA%22">Solomon DA</searchLink>; Department of Pathology, University of California, San Francisco, CA, USA. david.solomon@ucsf.edu.; Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, USA. david.solomon@ucsf.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220412041%22">Acta neuropathologica</searchLink> [Acta Neuropathol] 2020 Jun; Vol. 139 (6), pp. 1071-1088. <i>Date of Electronic Publication: </i>2020 Apr 17. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0412041 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0533 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200016322%22">00016322 </searchLink><i>NLM ISO Abbreviation: </i>Acta Neuropathol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=32303840 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00401-020-02155-5 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1071 Titles: – TitleFull: Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Mondal G – PersonEntity: Name: NameFull: Lee JC – PersonEntity: Name: NameFull: Ravindranathan A – PersonEntity: Name: NameFull: Villanueva-Meyer JE – PersonEntity: Name: NameFull: Tran QT – PersonEntity: Name: NameFull: Allen SJ – PersonEntity: Name: NameFull: Barreto J – PersonEntity: Name: NameFull: Gupta R – PersonEntity: Name: NameFull: Doo P – PersonEntity: Name: NameFull: Van Ziffle J – PersonEntity: Name: NameFull: Onodera C – PersonEntity: Name: NameFull: Devine P – PersonEntity: Name: NameFull: Grenert JP – PersonEntity: Name: NameFull: Samuel D – PersonEntity: Name: NameFull: Li R – PersonEntity: Name: NameFull: Metrock LK – PersonEntity: Name: NameFull: Jin LW – PersonEntity: Name: NameFull: Antony R – PersonEntity: Name: NameFull: Alashari M – PersonEntity: Name: NameFull: Cheshier S – PersonEntity: Name: NameFull: Whipple NS – PersonEntity: Name: NameFull: Bruggers C – PersonEntity: Name: NameFull: Raffel C – PersonEntity: Name: NameFull: Gupta N – PersonEntity: Name: NameFull: Kline CN – PersonEntity: Name: NameFull: Reddy A – PersonEntity: Name: NameFull: Banerjee A – PersonEntity: Name: NameFull: Hall MD – PersonEntity: Name: NameFull: Mehta MP – PersonEntity: Name: NameFull: Khatib Z – PersonEntity: Name: NameFull: Maher OM – PersonEntity: Name: NameFull: Brathwaite C – PersonEntity: Name: NameFull: Pekmezci M – PersonEntity: Name: NameFull: Phillips JJ – PersonEntity: Name: NameFull: Bollen AW – PersonEntity: Name: NameFull: Tihan T – PersonEntity: Name: NameFull: Lucas JT Jr – PersonEntity: Name: NameFull: Broniscer A – PersonEntity: Name: NameFull: Berger MS – PersonEntity: Name: NameFull: Perry A – PersonEntity: Name: NameFull: Orr BA – PersonEntity: Name: NameFull: Solomon DA IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2020 Jun Type: published Y: 2020 Identifiers: – Type: issn-electronic Value: 1432-0533 Numbering: – Type: volume Value: 139 – Type: issue Value: 6 Titles: – TitleFull: Acta neuropathologica Type: main |
| ResultId | 1 |
