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UFLC-MS/MS Determination and Population Pharmacokinetic Study of Tanshinol, Ginsenoside Rb1 and Rg1 in Rat Plasma After Oral Administration of Compound Danshen Dripping Pills.

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Title: UFLC-MS/MS Determination and Population Pharmacokinetic Study of Tanshinol, Ginsenoside Rb1 and Rg1 in Rat Plasma After Oral Administration of Compound Danshen Dripping Pills.
Authors: Jin T; Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin, 300410, China.; State Key Laboratory of Critical Technology in Innovative Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin, 300410, China.; Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, 210009, China., Liu Z; Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin, 300410, China.; State Key Laboratory of Critical Technology in Innovative Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin, 300410, China.; Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, 210009, China., Chu Y; Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin, 300410, China.; State Key Laboratory of Critical Technology in Innovative Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin, 300410, China., Ma X; Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin, 300410, China.; State Key Laboratory of Critical Technology in Innovative Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin, 300410, China., Li S; Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin, 300410, China.; State Key Laboratory of Critical Technology in Innovative Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin, 300410, China., Wang X; Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin, 300410, China.; State Key Laboratory of Critical Technology in Innovative Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin, 300410, China., Wang G; Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin, 300410, China.; State Key Laboratory of Critical Technology in Innovative Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin, 300410, China., Zhou S; Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin, 300410, China.; State Key Laboratory of Critical Technology in Innovative Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin, 300410, China., Sun H; Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin, 300410, China.; State Key Laboratory of Critical Technology in Innovative Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin, 300410, China.; Tasly Pharmaceuticals Inc, Rockville, MD, 20850, USA., Yang J; Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, 210009, China. yjcpu@yahoo.com.
Source: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2020 Aug; Vol. 45 (4), pp. 523-533.
Publication Type: Journal Article
Journal Info: Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print Cited Medium: Internet ISSN: 2107-0180 (Electronic) Linking ISSN: 03787966 NLM ISO Abbreviation: Eur J Drug Metab Pharmacokinet Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2107-0180
DOI:10.1007/s13318-020-00618-4