Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
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| Title: | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. |
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| Authors: | Magnussen HM; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Ahmed SF; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Sibbet GJ; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Hristova VA; Laboratory of Protein Dynamics and Signaling, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA., Nomura K; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Hock AK; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; AstraZeneca, AstraZeneca R&D, Innovative Medicines, Discovery Sciences, Darwin (Building 310), Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, UK., Archibald LJ; School of Chemistry, University of Glasgow, Joseph Black Building, G12 8QQ, Glasgow, UK., Jamieson AG; School of Chemistry, University of Glasgow, Joseph Black Building, G12 8QQ, Glasgow, UK., Fushman D; Department of Chemistry and Biochemistry, Center for Biomolecular Structure and Organization, University of Maryland, College Park, MD, 20742, USA., Vousden KH; The Francis Crick Institute, London, NW1 1AT, UK., Weissman AM; Laboratory of Protein Dynamics and Signaling, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA., Huang DT; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK. d.huang@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK. d.huang@beatson.gla.ac.uk. |
| Source: | Nature communications [Nat Commun] 2020 Apr 29; Vol. 11 (1), pp. 2094. Date of Electronic Publication: 2020 Apr 29. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-020-15783-y |
