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Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.

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Title: Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Authors: Magnussen HM; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Ahmed SF; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Sibbet GJ; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Hristova VA; Laboratory of Protein Dynamics and Signaling, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA., Nomura K; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Hock AK; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; AstraZeneca, AstraZeneca R&D, Innovative Medicines, Discovery Sciences, Darwin (Building 310), Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, UK., Archibald LJ; School of Chemistry, University of Glasgow, Joseph Black Building, G12 8QQ, Glasgow, UK., Jamieson AG; School of Chemistry, University of Glasgow, Joseph Black Building, G12 8QQ, Glasgow, UK., Fushman D; Department of Chemistry and Biochemistry, Center for Biomolecular Structure and Organization, University of Maryland, College Park, MD, 20742, USA., Vousden KH; The Francis Crick Institute, London, NW1 1AT, UK., Weissman AM; Laboratory of Protein Dynamics and Signaling, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA., Huang DT; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK. d.huang@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK. d.huang@beatson.gla.ac.uk.
Source: Nature communications [Nat Commun] 2020 Apr 29; Vol. 11 (1), pp. 2094. Date of Electronic Publication: 2020 Apr 29.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Magnussen+HM%22">Magnussen HM</searchLink>; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK.<br /><searchLink fieldCode="AU" term="%22Ahmed+SF%22">Ahmed SF</searchLink>; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Sibbet+GJ%22">Sibbet GJ</searchLink>; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Hristova+VA%22">Hristova VA</searchLink>; Laboratory of Protein Dynamics and Signaling, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Nomura+K%22">Nomura K</searchLink>; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK.<br /><searchLink fieldCode="AU" term="%22Hock+AK%22">Hock AK</searchLink>; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; AstraZeneca, AstraZeneca R&D, Innovative Medicines, Discovery Sciences, Darwin (Building 310), Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, UK.<br /><searchLink fieldCode="AU" term="%22Archibald+LJ%22">Archibald LJ</searchLink>; School of Chemistry, University of Glasgow, Joseph Black Building, G12 8QQ, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Jamieson+AG%22">Jamieson AG</searchLink>; School of Chemistry, University of Glasgow, Joseph Black Building, G12 8QQ, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Fushman+D%22">Fushman D</searchLink>; Department of Chemistry and Biochemistry, Center for Biomolecular Structure and Organization, University of Maryland, College Park, MD, 20742, USA.<br /><searchLink fieldCode="AU" term="%22Vousden+KH%22">Vousden KH</searchLink>; The Francis Crick Institute, London, NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Weissman+AM%22">Weissman AM</searchLink>; Laboratory of Protein Dynamics and Signaling, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Huang+DT%22">Huang DT</searchLink>; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK. d.huang@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK. d.huang@beatson.gla.ac.uk.
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