CRISPR-Cas9 generated Pompe knock-in murine model exhibits early-onset hypertrophic cardiomyopathy and skeletal muscle weakness.
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| Title: | CRISPR-Cas9 generated Pompe knock-in murine model exhibits early-onset hypertrophic cardiomyopathy and skeletal muscle weakness. |
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| Authors: | Huang JY; CHOC Children's Research Institute, Orange, CA, 92868, USA. jhuang@choc.org., Kan SH; CHOC Children's Research Institute, Orange, CA, 92868, USA., Sandfeld EK; CHOC Children's Research Institute, Orange, CA, 92868, USA., Dalton ND; Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Rangel AD; CHOC Children's Research Institute, Orange, CA, 92868, USA., Chan Y; Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Davis-Turak J; OnRamp BioInformatics, Inc., San Diego, CA, 92121, USA., Neumann J; Transgenic Mouse Facility, University of California Irvine, Irvine, CA, 92697, USA., Wang RY; Department of Pediatrics, University of California-Irvine School of Medicine, Irvine, CA, 92697, USA.; Division of Metabolic Disorders, CHOC Children's Specialists, Orange, CA, 92868, USA. |
| Source: | Scientific reports [Sci Rep] 2020 Jun 25; Vol. 10 (1), pp. 10321. Date of Electronic Publication: 2020 Jun 25. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-020-65259-8 |
