A rare variant of African ancestry activates 8q24 lncRNA hub by modulating cancer associated enhancer.
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| Title: | A rare variant of African ancestry activates 8q24 lncRNA hub by modulating cancer associated enhancer. |
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| Authors: | Walavalkar K; Genetics and Development, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India., Saravanan B; Genetics and Development, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India.; Sastra Deemed University, Thanjavur, Tamil Nadu, 613401, India., Singh AK; Genetics and Development, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India., Jayani RS; Howard Hughes Medical Institute, Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92037, USA., Nair A; Genetics and Development, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India.; Sastra Deemed University, Thanjavur, Tamil Nadu, 613401, India., Farooq U; Genetics and Development, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India.; Trans-Disciplinary University, IVRI road, Bangalore, Tamil Nadu, 560064, Karnataka, India., Islam Z; Genetics and Development, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India.; Sastra Deemed University, Thanjavur, Tamil Nadu, 613401, India., Soota D; Genetics and Development, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India., Mann R; Genetics and Development, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India., Shivaprasad PV; Genetics and Development, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India., Freedman ML; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.; The Eli and Edythe L. Broad Institute, Cambridge, MA, 02142, USA.; Centre for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Sabarinathan R; Genetics and Development, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90007, USA., Notani D; Genetics and Development, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India. dnotani@ncbs.res.in. |
| Source: | Nature communications [Nat Commun] 2020 Jul 17; Vol. 11 (1), pp. 3598. Date of Electronic Publication: 2020 Jul 17. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-020-17325-y |
