Allosteric targeting of the FFA2 receptor (GPR43) restores responsiveness of desensitized human neutrophils.

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Bibliographic Details
Title: Allosteric targeting of the FFA2 receptor (GPR43) restores responsiveness of desensitized human neutrophils.
Authors: Frei R; Institute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria., Nordlohne J; Bayer AG, Pharmaceuticals R&D, Preclinical Research, Pharma Research Center, Wuppertal, Germany., Hüser U; Bayer AG, Pharmaceuticals R&D, Preclinical Research, Pharma Research Center, Wuppertal, Germany., Hild S; Molecular, Cellular and Pharmacobiology Section, Institute of Pharmaceutical Biology, University of Bonn, Bonn, Germany., Schmidt J; Molecular, Cellular and Pharmacobiology Section, Institute of Pharmaceutical Biology, University of Bonn, Bonn, Germany., Eitner F; Bayer AG, Pharmaceuticals R&D, Preclinical Research, Pharma Research Center, Wuppertal, Germany., Grundmann M; Molecular, Cellular and Pharmacobiology Section, Institute of Pharmaceutical Biology, University of Bonn, Bonn, Germany.; Bayer AG, Pharmaceuticals R&D, Preclinical Research, Pharma Research Center, Wuppertal, Germany.
Source: Journal of leukocyte biology [J Leukoc Biol] 2021 Apr; Vol. 109 (4), pp. 741-751. Date of Electronic Publication: 2020 Aug 17.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8405628 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-3673 (Electronic) Linking ISSN: 07415400 NLM ISO Abbreviation: J Leukoc Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1938-3673
DOI:10.1002/JLB.2A0720-432R