Mechanistic Multilayer Quantitative Model for Nonlinear Pharmacokinetics, Target Occupancy and Pharmacodynamics (PK/TO/PD) Relationship of D-Amino Acid Oxidase Inhibitor, TAK-831 in Mice.

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Bibliographic Details
Title:	Mechanistic Multilayer Quantitative Model for Nonlinear Pharmacokinetics, Target Occupancy and Pharmacodynamics (PK/TO/PD) Relationship of D-Amino Acid Oxidase Inhibitor, TAK-831 in Mice.
Authors:	Yoneyama T; Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan. tomoki.yoneyama@takeda.com., Sato S; Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan., Sykes A; Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Cambridge Ltd, Cambridge, UK., Fradley R; Pharmacology, Takeda Cambridge Ltd, Cambridge, UK., Stafford S; Pharmacology, Takeda Cambridge Ltd, Cambridge, UK., Bechar S; Pharmacology, Takeda Cambridge Ltd, Cambridge, UK., Howley E; Pharmacology, Takeda Cambridge Ltd, Cambridge, UK., Patel T; Pharmacology, Takeda Cambridge Ltd, Cambridge, UK., Tagawa Y; Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan., Moriwaki T; Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan., Asahi S; Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan.
Source:	Pharmaceutical research [Pharm Res] 2020 Aug 05; Vol. 37 (8), pp. 164. Date of Electronic Publication: 2020 Aug 05.
Publication Type:	Journal Article
Journal Info:	Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE
Database:	MEDLINE Ultimate

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