Targeted IgMs agonize ocular targets with extended vitreal exposure.
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| Title: | Targeted IgMs agonize ocular targets with extended vitreal exposure. |
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| Authors: | Chen Y; Departments of Antibody Engineering, Genentech Inc ., South San Francisco, CA, USA., Paluch M; Departments of Protein Chemistry, Genentech Inc ., South San Francisco, CA, USA., Zorn JA; Departments of Structural Biology, Genentech Inc ., South San Francisco, CA, USA., Rajan S; Departments of Preclinical & Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc ., South San Francisco, CA, USA., Leonard B; Departments of Antibody Engineering, Genentech Inc ., South San Francisco, CA, USA., Estevez A; Departments of Structural Biology, Genentech Inc ., South San Francisco, CA, USA., Brady J; Departments of Molecular Oncology, Genentech Inc ., South San Francisco, CA, USA., Chiu H; Departments of Biochemical and Cellular Physiology, Genentech Inc ., South San Francisco, CA, USA., Phung W; Departments of Microchemistry Proteomics and Lipidomics, Genentech Inc ., South San Francisco, CA, USA., Famili A; Departments of Drug Development, Genentech Inc ., South San Francisco, CA, USA., Yan M; Departments of Molecular Oncology, Genentech Inc ., South San Francisco, CA, USA., Ciferri C; Departments of Structural Biology, Genentech Inc ., South San Francisco, CA, USA., Matsumoto ML; Departments of Structural Biology, Genentech Inc ., South San Francisco, CA, USA., Lazar GA; Departments of Antibody Engineering, Genentech Inc ., South San Francisco, CA, USA., Crowell S; Departments of Preclinical & Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc ., South San Francisco, CA, USA., Hass P; Departments of Protein Chemistry, Genentech Inc ., South San Francisco, CA, USA., Agard NJ; Departments of Antibody Engineering, Genentech Inc ., South San Francisco, CA, USA. |
| Source: | MAbs [MAbs] 2020 Jan-Dec; Vol. 12 (1), pp. 1818436. |
| Publication Type: | Journal Article; Video-Audio Media |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1942-0870 |
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| DOI: | 10.1080/19420862.2020.1818436 |
