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Targeted IgMs agonize ocular targets with extended vitreal exposure.

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Title: Targeted IgMs agonize ocular targets with extended vitreal exposure.
Authors: Chen Y; Departments of Antibody Engineering, Genentech Inc ., South San Francisco, CA, USA., Paluch M; Departments of Protein Chemistry, Genentech Inc ., South San Francisco, CA, USA., Zorn JA; Departments of Structural Biology, Genentech Inc ., South San Francisco, CA, USA., Rajan S; Departments of Preclinical & Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc ., South San Francisco, CA, USA., Leonard B; Departments of Antibody Engineering, Genentech Inc ., South San Francisco, CA, USA., Estevez A; Departments of Structural Biology, Genentech Inc ., South San Francisco, CA, USA., Brady J; Departments of Molecular Oncology, Genentech Inc ., South San Francisco, CA, USA., Chiu H; Departments of Biochemical and Cellular Physiology, Genentech Inc ., South San Francisco, CA, USA., Phung W; Departments of Microchemistry Proteomics and Lipidomics, Genentech Inc ., South San Francisco, CA, USA., Famili A; Departments of Drug Development, Genentech Inc ., South San Francisco, CA, USA., Yan M; Departments of Molecular Oncology, Genentech Inc ., South San Francisco, CA, USA., Ciferri C; Departments of Structural Biology, Genentech Inc ., South San Francisco, CA, USA., Matsumoto ML; Departments of Structural Biology, Genentech Inc ., South San Francisco, CA, USA., Lazar GA; Departments of Antibody Engineering, Genentech Inc ., South San Francisco, CA, USA., Crowell S; Departments of Preclinical & Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc ., South San Francisco, CA, USA., Hass P; Departments of Protein Chemistry, Genentech Inc ., South San Francisco, CA, USA., Agard NJ; Departments of Antibody Engineering, Genentech Inc ., South San Francisco, CA, USA.
Source: MAbs [MAbs] 2020 Jan-Dec; Vol. 12 (1), pp. 1818436.
Publication Type: Journal Article; Video-Audio Media
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeted IgMs agonize ocular targets with extended vitreal exposure.
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