Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect.
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| Title: | Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect. |
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| Authors: | Bachireddy P; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Ennis C; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA., Nguyen VN; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA., Gohil SH; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Academic Haematology, University College London, London WC1E 6BT, UK., Clement K; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA., Shukla SA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Forman J; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Barkas N; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Freeman S; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Bavli N; Division of Hematology and Oncology, UT Southwestern, Dallas, TX 75390, USA., Elagina L; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Leshchiner I; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Mohammad AW; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Mathewson ND; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Keskin DB; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Rassenti LZ; Moores Cancer Center, University of California, San Diego, La Jolla, CA 92037, USA., Kipps TJ; Moores Cancer Center, University of California, San Diego, La Jolla, CA 92037, USA., Brown JR; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Getz G; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA., Ho VT; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Gnirke A; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Neuberg D; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Soiffer RJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Ritz J; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Alyea EP; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Kharchenko PV; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.; Harvard Stem Cell Institute, Cambridge, MA 02138, USA., Wu CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA. cwu@partners.org.; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2020 Sep 16; Vol. 12 (561). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.abb7661 |
