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Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect.

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Title: Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect.
Authors: Bachireddy P; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Ennis C; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA., Nguyen VN; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA., Gohil SH; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Academic Haematology, University College London, London WC1E 6BT, UK., Clement K; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA., Shukla SA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Forman J; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Barkas N; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Freeman S; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Bavli N; Division of Hematology and Oncology, UT Southwestern, Dallas, TX 75390, USA., Elagina L; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Leshchiner I; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Mohammad AW; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Mathewson ND; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Keskin DB; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Rassenti LZ; Moores Cancer Center, University of California, San Diego, La Jolla, CA 92037, USA., Kipps TJ; Moores Cancer Center, University of California, San Diego, La Jolla, CA 92037, USA., Brown JR; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Getz G; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA., Ho VT; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Gnirke A; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Neuberg D; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Soiffer RJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Ritz J; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Alyea EP; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Kharchenko PV; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.; Harvard Stem Cell Institute, Cambridge, MA 02138, USA., Wu CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA. cwu@partners.org.; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Source: Science translational medicine [Sci Transl Med] 2020 Sep 16; Vol. 12 (561).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect.
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  Data: <searchLink fieldCode="AU" term="%22Bachireddy+P%22">Bachireddy P</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Ennis+C%22">Ennis C</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+VN%22">Nguyen VN</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.<br /><searchLink fieldCode="AU" term="%22Gohil+SH%22">Gohil SH</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; 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Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Bavli+N%22">Bavli N</searchLink>; Division of Hematology and Oncology, UT Southwestern, Dallas, TX 75390, USA.<br /><searchLink fieldCode="AU" term="%22Elagina+L%22">Elagina L</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Leshchiner+I%22">Leshchiner I</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Mohammad+AW%22">Mohammad AW</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Mathewson+ND%22">Mathewson ND</searchLink>; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.<br /><searchLink fieldCode="AU" term="%22Keskin+DB%22">Keskin DB</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Rassenti+LZ%22">Rassenti LZ</searchLink>; Moores Cancer Center, University of California, San Diego, La Jolla, CA 92037, USA.<br /><searchLink fieldCode="AU" term="%22Kipps+TJ%22">Kipps TJ</searchLink>; Moores Cancer Center, University of California, San Diego, La Jolla, CA 92037, USA.<br /><searchLink fieldCode="AU" term="%22Brown+JR%22">Brown JR</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Getz+G%22">Getz G</searchLink>; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Ho+VT%22">Ho VT</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Gnirke+A%22">Gnirke A</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Neuberg+D%22">Neuberg D</searchLink>; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA 02215, USA.<br /><searchLink fieldCode="AU" term="%22Soiffer+RJ%22">Soiffer RJ</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Ritz+J%22">Ritz J</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Alyea+EP%22">Alyea EP</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Kharchenko+PV%22">Kharchenko PV</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.; Harvard Stem Cell Institute, Cambridge, MA 02138, USA.<br /><searchLink fieldCode="AU" term="%22Wu+CJ%22">Wu CJ</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA. cwu@partners.org.; Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
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