An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice.

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Title: An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice.
Authors: Zhang JF; Department of Pharmacology, University of California, San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA., Liu B; The Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.; The Kavli Neuroscience Discovery Institute, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Hong I; The Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.; The Kavli Neuroscience Discovery Institute, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Mo A; Department of Pharmacology, University of California, San Diego, La Jolla, CA, USA., Roth RH; The Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.; The Kavli Neuroscience Discovery Institute, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Neurosurgery, Stanford University School of Medicine, Palo Alto, CA, USA., Tenner B; Department of Pharmacology, University of California, San Diego, La Jolla, CA, USA., Lin W; Department of Pharmacology, University of California, San Diego, La Jolla, CA, USA., Zhang JZ; Department of Pharmacology, University of California, San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA., Molina RS; Department of Cell Biology and Neuroscience, Montana State University, Bozeman, MT, USA., Drobizhev M; Department of Cell Biology and Neuroscience, Montana State University, Bozeman, MT, USA., Hughes TE; Department of Cell Biology and Neuroscience, Montana State University, Bozeman, MT, USA., Tian L; Department of Biochemistry and Molecular Medicine, University of California, Davis, Sacramento, CA, USA., Huganir RL; The Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. rhuganir@jhmi.edu.; The Kavli Neuroscience Discovery Institute, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. rhuganir@jhmi.edu., Mehta S; Department of Pharmacology, University of California, San Diego, La Jolla, CA, USA. sohum@ucsd.edu., Zhang J; Department of Pharmacology, University of California, San Diego, La Jolla, CA, USA. jzhang32@ucsd.edu.; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA. jzhang32@ucsd.edu.; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, USA. jzhang32@ucsd.edu.
Source: Nature chemical biology [Nat Chem Biol] 2021 Jan; Vol. 17 (1), pp. 39-46. Date of Electronic Publication: 2020 Sep 28.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1552-4469
DOI:10.1038/s41589-020-00660-y