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Combined proteomic and transcriptomic approaches reveal externalized keratin 8 as a potential therapeutic target involved in invasiveness of head and neck cancers.

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Title: Combined proteomic and transcriptomic approaches reveal externalized keratin 8 as a potential therapeutic target involved in invasiveness of head and neck cancers.
Authors: Albaret MA; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France., Paré A; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France; Department of Maxillofacial and Plastic surgery, CHRU of Tours, 37170 Chambray-lés-Tours, France; University of François Rabelais, School of Medicine, Tours F-37032, France., Malet L; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France., De Souza G; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France., Lavergne E; Biostatistics Unit, Centre Léon Bérard, 69373 Lyon, France., Goga D; Department of Maxillofacial and Plastic surgery, CHRU of Tours, 37170 Chambray-lés-Tours, France; University of François Rabelais, School of Medicine, Tours F-37032, France., De Pinieux G; Department of Pathology, CHRU of Tours, 37170 Chambray-lés-Tours, France; University of François Rabelais, School of Medicine, Tours F-37032, France., Castellier C; Department of Pathology, CHRU of Tours, 37170 Chambray-lés-Tours, France; University of François Rabelais, School of Medicine, Tours F-37032, France., Swalduz A; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France; Department of Medicine, Centre Léon Bérard, 69373 Lyon, France., Robin V; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France., Lavergne V; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France., Mertani HC; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France., Treilleux I; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France; Department of Pathology, Centre Léon Bérard, 69373 Lyon, France., Vermot-Desroches C; IDD BIOTECH, Bâtiment Accinov, 317 avenue Jean Jaurès, 69007, Lyon, France., Diaz JJ; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France. Electronic address: jean-jacques.diaz@lyon.unicancer.fr., Saintigny P; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France; Department of Medicine, Centre Léon Bérard, 69373 Lyon, France. Electronic address: pierre.saintigny@lyon.unicancer.fr.
Source: Translational oncology [Transl Oncol] 2021 Jan; Vol. 14 (1), pp. 100878. Date of Electronic Publication: 2020 Sep 30.
Publication Type: Journal Article
Journal Info: Publisher: Neoplasia Press Country of Publication: United States NLM ID: 101472619 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1936-5233 (Print) Linking ISSN: 19365233 NLM ISO Abbreviation: Transl Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1936-5233
DOI:10.1016/j.tranon.2020.100878