Combined proteomic and transcriptomic approaches reveal externalized keratin 8 as a potential therapeutic target involved in invasiveness of head and neck cancers.

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Title: Combined proteomic and transcriptomic approaches reveal externalized keratin 8 as a potential therapeutic target involved in invasiveness of head and neck cancers.
Authors: Albaret MA; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France., Paré A; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France; Department of Maxillofacial and Plastic surgery, CHRU of Tours, 37170 Chambray-lés-Tours, France; University of François Rabelais, School of Medicine, Tours F-37032, France., Malet L; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France., De Souza G; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France., Lavergne E; Biostatistics Unit, Centre Léon Bérard, 69373 Lyon, France., Goga D; Department of Maxillofacial and Plastic surgery, CHRU of Tours, 37170 Chambray-lés-Tours, France; University of François Rabelais, School of Medicine, Tours F-37032, France., De Pinieux G; Department of Pathology, CHRU of Tours, 37170 Chambray-lés-Tours, France; University of François Rabelais, School of Medicine, Tours F-37032, France., Castellier C; Department of Pathology, CHRU of Tours, 37170 Chambray-lés-Tours, France; University of François Rabelais, School of Medicine, Tours F-37032, France., Swalduz A; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France; Department of Medicine, Centre Léon Bérard, 69373 Lyon, France., Robin V; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France., Lavergne V; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France., Mertani HC; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France., Treilleux I; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France; Department of Pathology, Centre Léon Bérard, 69373 Lyon, France., Vermot-Desroches C; IDD BIOTECH, Bâtiment Accinov, 317 avenue Jean Jaurès, 69007, Lyon, France., Diaz JJ; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France. Electronic address: jean-jacques.diaz@lyon.unicancer.fr., Saintigny P; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France; Department of Medicine, Centre Léon Bérard, 69373 Lyon, France. Electronic address: pierre.saintigny@lyon.unicancer.fr.
Source: Translational oncology [Transl Oncol] 2021 Jan; Vol. 14 (1), pp. 100878. Date of Electronic Publication: 2020 Sep 30.
Publication Type: Journal Article
Journal Info: Publisher: Neoplasia Press Country of Publication: United States NLM ID: 101472619 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1936-5233 (Print) Linking ISSN: 19365233 NLM ISO Abbreviation: Transl Oncol Subsets: PubMed not MEDLINE
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  Data: Combined proteomic and transcriptomic approaches reveal externalized keratin 8 as a potential therapeutic target involved in invasiveness of head and neck cancers.
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  Data: <searchLink fieldCode="AU" term="%22Albaret+MA%22">Albaret MA</searchLink>; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France.<br /><searchLink fieldCode="AU" term="%22Paré+A%22">Paré A</searchLink>; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France; Department of Maxillofacial and Plastic surgery, CHRU of Tours, 37170 Chambray-lés-Tours, France; University of François Rabelais, School of Medicine, Tours F-37032, France.<br /><searchLink fieldCode="AU" term="%22Malet+L%22">Malet L</searchLink>; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France.<br /><searchLink fieldCode="AU" term="%22De+Souza+G%22">De Souza G</searchLink>; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France.<br /><searchLink fieldCode="AU" term="%22Lavergne+E%22">Lavergne E</searchLink>; Biostatistics Unit, Centre Léon Bérard, 69373 Lyon, France.<br /><searchLink fieldCode="AU" term="%22Goga+D%22">Goga D</searchLink>; Department of Maxillofacial and Plastic surgery, CHRU of Tours, 37170 Chambray-lés-Tours, France; University of François Rabelais, School of Medicine, Tours F-37032, France.<br /><searchLink fieldCode="AU" term="%22De+Pinieux+G%22">De Pinieux G</searchLink>; Department of Pathology, CHRU of Tours, 37170 Chambray-lés-Tours, France; University of François Rabelais, School of Medicine, Tours F-37032, France.<br /><searchLink fieldCode="AU" term="%22Castellier+C%22">Castellier C</searchLink>; Department of Pathology, CHRU of Tours, 37170 Chambray-lés-Tours, France; University of François Rabelais, School of Medicine, Tours F-37032, France.<br /><searchLink fieldCode="AU" term="%22Swalduz+A%22">Swalduz A</searchLink>; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France; Department of Medicine, Centre Léon Bérard, 69373 Lyon, France.<br /><searchLink fieldCode="AU" term="%22Robin+V%22">Robin V</searchLink>; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France.<br /><searchLink fieldCode="AU" term="%22Lavergne+V%22">Lavergne V</searchLink>; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France.<br /><searchLink fieldCode="AU" term="%22Mertani+HC%22">Mertani HC</searchLink>; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France.<br /><searchLink fieldCode="AU" term="%22Treilleux+I%22">Treilleux I</searchLink>; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France; Department of Pathology, Centre Léon Bérard, 69373 Lyon, France.<br /><searchLink fieldCode="AU" term="%22Vermot-Desroches+C%22">Vermot-Desroches C</searchLink>; IDD BIOTECH, Bâtiment Accinov, 317 avenue Jean Jaurès, 69007, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Diaz+JJ%22">Diaz JJ</searchLink>; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France. Electronic address: jean-jacques.diaz@lyon.unicancer.fr.<br /><searchLink fieldCode="AU" term="%22Saintigny+P%22">Saintigny P</searchLink>; Univ Lyon, Université Claude Bernard Lyon 1, INSERM U1052, CNRS UMR5286, Centre Léon Bérard, Cancer Research Center of Lyon, 69008 Lyon, France; Department of Translational Research and Innovation, Centre Léon Bérard, 69373 Lyon, France; Department of Medicine, Centre Léon Bérard, 69373 Lyon, France. Electronic address: pierre.saintigny@lyon.unicancer.fr.
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