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CRISPR/Cas9-engineered Gad1 elimination in rats leads to complex behavioral changes: implications for schizophrenia.

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Title: CRISPR/Cas9-engineered Gad1 elimination in rats leads to complex behavioral changes: implications for schizophrenia.
Authors: Fujihara K; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan. psy_fujihara@gunma-u.ac.jp.; Department of Psychiatry and Neuroscience, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan. psy_fujihara@gunma-u.ac.jp., Yamada K; Institute of Psychology and Behavioral Neuroscience, University of Tsukuba, Tsukuba City, Ibaraki, 305-8577, Japan., Ichitani Y; Institute of Psychology and Behavioral Neuroscience, University of Tsukuba, Tsukuba City, Ibaraki, 305-8577, Japan., Kakizaki T; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan., Jiang W; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan., Miyata S; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan., Suto T; Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan., Kato D; Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan., Saito S; Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan., Watanabe M; Department of Anatomy, Faculty of Medicine, Hokkaido University, Sapporo City, Hokkaido, 060-8638, Japan., Kajita Y; Department of Physiology, Graduate School of Medicine, Tohoku University, Sendai City, Miyagi, 980-8575, Japan., Ohshiro T; Department of Physiology, Graduate School of Medicine, Tohoku University, Sendai City, Miyagi, 980-8575, Japan., Mushiake H; Department of Physiology, Graduate School of Medicine, Tohoku University, Sendai City, Miyagi, 980-8575, Japan., Miyasaka Y; Institute of Experimental Animal Sciences, Graduate School of Medicine, Osaka University, Suita City, Osaka, 565-0871, Japan., Mashimo T; Institute of Experimental Animal Sciences, Graduate School of Medicine, Osaka University, Suita City, Osaka, 565-0871, Japan.; Laboratory Animal Research Center, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan., Yasuda H; Division of Physiology, Faculty of Medicine, Saga University, Saga City, Saga, 849-8501, Japan., Yanagawa Y; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan. yuchio@gunma-u.ac.jp.
Source: Translational psychiatry [Transl Psychiatry] 2020 Dec 08; Vol. 10 (1), pp. 426. Date of Electronic Publication: 2020 Dec 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CRISPR/Cas9-engineered Gad1 elimination in rats leads to complex behavioral changes: implications for schizophrenia.
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  Data: <searchLink fieldCode="AU" term="%22Fujihara+K%22">Fujihara K</searchLink>; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan. psy_fujihara@gunma-u.ac.jp.; Department of Psychiatry and Neuroscience, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan. psy_fujihara@gunma-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Yamada+K%22">Yamada K</searchLink>; Institute of Psychology and Behavioral Neuroscience, University of Tsukuba, Tsukuba City, Ibaraki, 305-8577, Japan.<br /><searchLink fieldCode="AU" term="%22Ichitani+Y%22">Ichitani Y</searchLink>; Institute of Psychology and Behavioral Neuroscience, University of Tsukuba, Tsukuba City, Ibaraki, 305-8577, Japan.<br /><searchLink fieldCode="AU" term="%22Kakizaki+T%22">Kakizaki T</searchLink>; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan.<br /><searchLink fieldCode="AU" term="%22Jiang+W%22">Jiang W</searchLink>; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan.<br /><searchLink fieldCode="AU" term="%22Miyata+S%22">Miyata S</searchLink>; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan.<br /><searchLink fieldCode="AU" term="%22Suto+T%22">Suto T</searchLink>; Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+D%22">Kato D</searchLink>; Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan.<br /><searchLink fieldCode="AU" term="%22Saito+S%22">Saito S</searchLink>; Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan.<br /><searchLink fieldCode="AU" term="%22Watanabe+M%22">Watanabe M</searchLink>; Department of Anatomy, Faculty of Medicine, Hokkaido University, Sapporo City, Hokkaido, 060-8638, Japan.<br /><searchLink fieldCode="AU" term="%22Kajita+Y%22">Kajita Y</searchLink>; Department of Physiology, Graduate School of Medicine, Tohoku University, Sendai City, Miyagi, 980-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Ohshiro+T%22">Ohshiro T</searchLink>; Department of Physiology, Graduate School of Medicine, Tohoku University, Sendai City, Miyagi, 980-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Mushiake+H%22">Mushiake H</searchLink>; Department of Physiology, Graduate School of Medicine, Tohoku University, Sendai City, Miyagi, 980-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Miyasaka+Y%22">Miyasaka Y</searchLink>; Institute of Experimental Animal Sciences, Graduate School of Medicine, Osaka University, Suita City, Osaka, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Mashimo+T%22">Mashimo T</searchLink>; Institute of Experimental Animal Sciences, Graduate School of Medicine, Osaka University, Suita City, Osaka, 565-0871, Japan.; Laboratory Animal Research Center, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.<br /><searchLink fieldCode="AU" term="%22Yasuda+H%22">Yasuda H</searchLink>; Division of Physiology, Faculty of Medicine, Saga University, Saga City, Saga, 849-8501, Japan.<br /><searchLink fieldCode="AU" term="%22Yanagawa+Y%22">Yanagawa Y</searchLink>; Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi City, Gunma, 371-8511, Japan. yuchio@gunma-u.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%22101562664%22">Translational psychiatry</searchLink> [Transl Psychiatry] 2020 Dec 08; Vol. 10 (1), pp. 426. <i>Date of Electronic Publication: </i>2020 Dec 08.
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