HM30181A, a potent P-glycoprotein inhibitor, potentiates the absorption and in vivo antitumor efficacy of paclitaxel in an orthotopic brain tumor model.

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Title: HM30181A, a potent P-glycoprotein inhibitor, potentiates the absorption and in vivo antitumor efficacy of paclitaxel in an orthotopic brain tumor model.
Authors: Zeng W; State Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China., Kwan Law BY; State Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China., Wai Wong VK; State Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China., Bik Chan DS; Athenex Hong Kong Innovative Limited, Hong Kong, China., Fai Mok SW; State Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China.; Faculty of Medicine, Macau University of Science and Technology, Macau, China., Ying Gao JJ; State Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China., Yan Ho RK; Faculty of Medicine, Macau University of Science and Technology, Macau, China., Liang X; Athenex Hong Kong Innovative Limited, Hong Kong, China., Li JH; Athenex Hong Kong Innovative Limited, Hong Kong, China., Lee MT; Athenex Hong Kong Innovative Limited, Hong Kong, China., Yoon WL; Athenex Hong Kong Innovative Limited, Hong Kong, China., Smolinski MP; Athenex Inc., New York 14203, USA., Nam Lau JY; Athenex Hong Kong Innovative Limited, Hong Kong, China., Kei Lam CW; Faculty of Medicine, Macau University of Science and Technology, Macau, China., Fok M; Faculty of Medicine, Macau University of Science and Technology, Macau, China.
Source: Cancer biology & medicine [Cancer Biol Med] 2020 Nov 15; Vol. 17 (4), pp. 986-1001. Date of Electronic Publication: 2020 Dec 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Chinese Anti-Cancer Association Country of Publication: China NLM ID: 101588850 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2095-3941 (Print) Linking ISSN: 20953941 NLM ISO Abbreviation: Cancer Biol Med
Database: MEDLINE Ultimate
Description
ISSN:2095-3941
DOI:10.20892/j.issn.2095-3941.2020.0128