Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors.

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Title: Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors.
Authors: Strong KL; Department of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.; Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States., Epplin MP; Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States., Ogden KK; Department of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States., Burger PB; Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States., Kaiser TM; Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States., Wilding TJ; Department of Cell Biology and Physiology, Washington University, St Louis, Missouri 63110, United States., Kusumoto H; Department of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States., Camp CR; Department of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States., Shaulsky G; Department of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States., Bhattacharya S; Department of Drug Discovery and Development, Auburn University, Auburn, Alabama 36849, United States., Perszyk RE; Department of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States., Menaldino DS; Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States., McDaniel MJ; Department of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States., Zhang J; Department of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States., Le P; Department of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States., Banke TG; Department of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States., Hansen KB; Department of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.; Center for Biomolecular Structure and Dynamics, Center for Structural and Functional Neuroscience, Division for Biological Sciences, University of Montana, 32 Campus Drive, Missoula, Montana 59812, United States., Huettner JE; Department of Cell Biology and Physiology, Washington University, St Louis, Missouri 63110, United States., Liotta DC; Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States., Traynelis SF; Department of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.
Source: ACS chemical neuroscience [ACS Chem Neurosci] 2021 Jan 06; Vol. 12 (1), pp. 79-98. Date of Electronic Publication: 2020 Dec 16.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1948-7193
DOI:10.1021/acschemneuro.0c00561