Development of a porcine model of phenylketonuria with a humanized R408W mutation for gene editing.
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| Title: | Development of a porcine model of phenylketonuria with a humanized R408W mutation for gene editing. |
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| Authors: | Kaiser RA; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America.; Midwest Fetal Care Center, Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota, United States of America., Carlson DF; Recombinetics, Inc., St. Paul, Minnesota, United States of America., Allen KL; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America., Webster DA; Recombinetics, Inc., St. Paul, Minnesota, United States of America., VanLith CJ; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America., Nicolas CT; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America.; Faculty of Medicine, University of Barcelona, Barcelona, Spain., Hillin LG; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America., Yu Y; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America., Kaiser CW; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America., Wahoff WR; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America., Hickey RD; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America.; Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America., Watson AL; Recombinetics, Inc., St. Paul, Minnesota, United States of America., Winn SR; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, Oregon, United States of America., Thöny B; Department of Pediatrics, University of Zurich, Zurich, Switzerland., Kern DR; Recombinetics, Inc., St. Paul, Minnesota, United States of America., Harding CO; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, Oregon, United States of America., Lillegard JB; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America.; Midwest Fetal Care Center, Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota, United States of America.; Pediatric Surgical Associates, Minneapolis, Minnesota, United States of America. |
| Source: | PloS one [PLoS One] 2021 Jan 25; Vol. 16 (1), pp. e0245831. Date of Electronic Publication: 2021 Jan 25 (Print Publication: 2021). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0245831 |
