Sepsis is associated with mitochondrial DNA damage and a reduced mitochondrial mass in the kidney of patients with sepsis-AKI.

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Title: Sepsis is associated with mitochondrial DNA damage and a reduced mitochondrial mass in the kidney of patients with sepsis-AKI.
Authors: van der Slikke EC; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, EB70, 9700 RB, Groningen, The Netherlands., Star BS; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, EB70, 9700 RB, Groningen, The Netherlands., van Meurs M; Department of Critical Care, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Pathology and Medical Biology, Medical Biology Section, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Henning RH; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, EB70, 9700 RB, Groningen, The Netherlands., Moser J; Department of Critical Care, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Pathology and Medical Biology, Medical Biology Section, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Bouma HR; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, EB70, 9700 RB, Groningen, The Netherlands. h.r.bouma@umcg.nl.; Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. h.r.bouma@umcg.nl.
Source: Critical care (London, England) [Crit Care] 2021 Jan 25; Vol. 25 (1), pp. 36. Date of Electronic Publication: 2021 Jan 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 9801902 Publication Model: Electronic Cited Medium: Internet ISSN: 1466-609X (Electronic) Linking ISSN: 13648535 NLM ISO Abbreviation: Crit Care Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1466-609X
DOI:10.1186/s13054-020-03424-1