Safety and Efficacy of Human Chorionic Gonadotropin Hormone-Derivative EA-230 in Cardiac Surgery Patients: A Randomized Double-Blind Placebo-Controlled Study.

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Title: Safety and Efficacy of Human Chorionic Gonadotropin Hormone-Derivative EA-230 in Cardiac Surgery Patients: A Randomized Double-Blind Placebo-Controlled Study.
Authors: van Groenendael R; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Cardiothoracic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.; Exponential Biotherapies, Inc. (EBI), The Hague, The Netherlands., Beunders R; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Cardiothoracic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.; Exponential Biotherapies, Inc. (EBI), The Hague, The Netherlands., Hemelaar P; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., Hofland J; Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, The Netherlands., Morshuis WJ; Department of Cardiothoracic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands., van der Hoeven JG; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Cardiothoracic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.; Exponential Biotherapies, Inc. (EBI), The Hague, The Netherlands., Gerretsen J; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., Wensvoort G; Exponential Biotherapies, Inc. (EBI), The Hague, The Netherlands., Kooistra EJ; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Cardiothoracic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.; Exponential Biotherapies, Inc. (EBI), The Hague, The Netherlands., Claassen WJ; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands., Waanders D; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands., Lamberts MGA; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands., Buijsse LSE; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands., Kox M; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Cardiothoracic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.; Exponential Biotherapies, Inc. (EBI), The Hague, The Netherlands., van Eijk LT; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Cardiothoracic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.; Exponential Biotherapies, Inc. (EBI), The Hague, The Netherlands., Pickkers P; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Cardiothoracic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.; Exponential Biotherapies, Inc. (EBI), The Hague, The Netherlands.
Source: Critical care medicine [Crit Care Med] 2021 May 01; Vol. 49 (5), pp. 790-803.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0355501 Publication Model: Print Cited Medium: Internet ISSN: 1530-0293 (Electronic) Linking ISSN: 00903493 NLM ISO Abbreviation: Crit Care Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1530-0293
DOI:10.1097/CCM.0000000000004847