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Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.

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Title: Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
Authors: Muus C; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA. muus@broadinstitute.org.; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA. muus@broadinstitute.org., Luecken MD; Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany. malte.luecken@helmholtz-muenchen.de., Eraslan G; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sikkema L; Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany., Waghray A; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.; Departments of Internal Medicine and Pediatrics, Pulmonary and Critical Care Unit, Massachusetts General Hospital, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Heimberg G; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kobayashi Y; Department of Cell Biology, Duke University Medical School, Durham, NC, USA., Vaishnav ED; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Subramanian A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Smillie C; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Jagadeesh KA; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Duong ET; Division of Respiratory Medicine, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Fiskin E; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Torlai Triglia E; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ansari M; Comprehensive Pneumology Center (CPC)/Institute of Lung Biology and Disease (ILBD), Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany.; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany., Cai P; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lin B; Departments of Internal Medicine and Pediatrics, Pulmonary and Critical Care Unit, Massachusetts General Hospital, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA., Buchanan J; Center for Epigenomics, University of California San Diego School of Medicine, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA., Chen S; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Shu J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Haber AL; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Chung H; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Montoro DT; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Adams T; Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA., Aliee H; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany., Allon SJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering and Science & Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Andrusivova Z; SciLifeLab, Department of Gene Technology, KTH Royal Institute of Technology, Stockolm, Sweden., Angelidis I; Comprehensive Pneumology Center (CPC)/Institute of Lung Biology and Disease (ILBD), Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany., Ashenberg O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bassler K; Department for Genomics & Immunoregulation, LIMES-Institute, University of Bonn, Bonn, Germany., Bécavin C; Université Côte d'Azur, CNRS, IPMC, Sophia-Antipolis, France., Benhar I; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bergenstråhle J; SciLifeLab, Department of Gene Technology, KTH Royal Institute of Technology, Stockolm, Sweden., Bergenstråhle L; SciLifeLab, Department of Gene Technology, KTH Royal Institute of Technology, Stockolm, Sweden., Bolt L; Wellcome Sanger Institute, Hinxton, UK., Braun E; Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Bui LT; Translational Genomics Research Institute, Phoenix, AZ, USA., Callori S; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.; Bioinformatics Program, Boston University School of Medicine, Boston, MA, USA., Chaffin M; Precision Cardiology Laboratory, The Broad Institute, Cambridge, MA, USA., Chichelnitskiy E; Institute of Transplant Immunology, Hannover Medical School, MHH, Hannover, Germany.; German Center for Infectious Diseases (DZIF), Braunschweig, Germany., Chiou J; Biomedical Sciences Graduate Program, University of California, San Diego, La Jolla, CA, USA., Conlon TM; Comprehensive Pneumology Center (CPC)/Institute of Lung Biology and Disease (ILBD), Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany., Cuoco MS; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Cuomo ASE; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK., Deprez M; Université Côte d'Azur, CNRS, IPMC, Sophia-Antipolis, France., Duclos G; Boston University School of Medicine, Boston, MA, USA., Fine D; Boston University Medical Center, Boston, MA, USA., Fischer DS; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany., Ghazanfar S; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Gillich A; Department of Biochemistry and Wall Center for Pulmonary Vascular Disease, Stanford, CA, USA., Giotti B; Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Gould J; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Guo M; Divisions of Pulmonary Biology; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Gutierrez AJ; Translational Genomics Research Institute, Phoenix, AZ, USA., Habermann AC; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Harvey T; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., He P; Wellcome Sanger Institute, Hinxton, UK., Hou X; Center for Epigenomics, University of California-San Diego School of Medicine, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California-San Diego School of Medicine, La Jolla, CA, USA., Hu L; Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Hu Y; Division of Pulmonary Sciences and Critical Care Medicine, School of Medicine, University of Colorado, Aurora, CO, USA., Jaiswal A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ji L; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, SAR, China., Jiang P; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, SAR, China., Kapellos TS; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Kuo CS; Division of Pulmonary Medicine, Department of Pediatrics, Stanford University, Stanford, CA, USA., Larsson L; SciLifeLab, Department of Gene Technology, KTH Royal Institute of Technology, Stockholm, Sweden., Leney-Greene MA; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lim K; Gurdon Institute, University of Cambridge, Cambridge, UK., Litviňuková M; Cellular Genetics Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Ludwig LS; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Lukassen S; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; Berlin Institute of Health (BIH), Center for Digital Health, Berlin, Germany., Luo W; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Maatz H; Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Madissoon E; European Molecular Biology Laboratory-European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, UK.; Wellcome Sanger Institute, Cellular Genetics Programme Wellcome Genome Campus, Hinxton, UK., Mamanova L; Wellcome Sanger Institute, Hinxton, UK., Manakongtreecheep K; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Charlestown, MA, USA., Leroy S; Pulmonology Department, Université Côte d'Azur, CHU Nice, Nice, France.; CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Sophia-Antipolis, France., Mayr CH; Helmholtz Zentrum München, Institute of Lung Biology and Disease, Group Systems Medicine of Chronic Lung Disease, Member of the German Center for Lung Research (DZL), Munich, Germany., Mbano IM; Africa Health Research Institute, Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of Kwazulu Natal, Durban, South Africa., McAdams AM; Department of Ophthalmology, Harvard Medical School and Massachusetts Eye and Ear, Boston, MA, USA., Nabhan AN; Department of Biochemistry and Wall Center for Pulmonary Vascular Disease, Stanford, CA, USA., Nyquist SK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Computational and Systems Biology, CSAIL, Institute for Medical Engineering and Science & Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Penland L; Department of Biochemistry and Wall Center for Pulmonary Vascular Disease, Stanford, CA, USA., Poirion OB; Center for Epigenomics, University of California-San Diego School of Medicine, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California-San Diego School of Medicine, La Jolla, CA, USA., Poli S; Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA., Qi C; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Queen R; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, International Centre for Life, Newcastle upon Tyne, UK., Reichart D; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Department of Cardiology, University Heart & Vascular Center, University of Hamburg, Hamburg, Germany., Rosas I; Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA., Schupp JC; Section of Pulmonary, Critical Care, and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA., Shea CV; Division of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Shi X; Division of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.; Bioinformatics Program, Boston University, Boston, MA, USA., Sinha R; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA, USA., Sit RV; Department of Biochemistry and Wall Center for Pulmonary Vascular Disease, Stanford, CA, USA., Slowikowski K; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Charlestown, MA, USA., Slyper M; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Smith NP; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA., Sountoulidis A; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden., Strunz M; Comprehensive Pneumology Center (CPC) and Institute of Lung Biology and Disease (ILBD), Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany., Sullivan TB; Lahey Hospital & Medical Center, Burlington, MA, USA., Sun D; Gurdon Institute, University of Cambridge, Cambridge, UK., Talavera-López C; Cellular Genetics Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Tan P; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tantivit J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Charlestown, MA, USA., Travaglini KJ; Department of Biochemistry and Wall Center for Pulmonary Vascular Disease, Stanford, CA, USA., Tucker NR; Precision Cardiology Laboratory, The Broad Institute, Cambridge, MA, USA.; Masonic Medical Research Institute, Utica, NY, USA., Vernon KA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Wadsworth MH; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering and Science, Department of Chemistry & Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Waldman J; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Wang X; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Xu K; Division of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Yan W; Center for Brain Science, Harvard University, Cambridge, MA, USA.; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA., Zhao W; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ziegler CGK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Harvard-MIT Health Sciences and Technology, Institute for Medical Engineering and Science, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
Corporate Authors: NHLBI LungMap Consortium, Human Cell Atlas Lung Biological Network
Source: Nature medicine [Nat Med] 2021 Mar; Vol. 27 (3), pp. 546-559. Date of Electronic Publication: 2021 Mar 02.
Publication Type: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
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  Data: <searchLink fieldCode="AU" term="%22Muus+C%22">Muus C</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA. muus@broadinstitute.org.; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA. muus@broadinstitute.org.<br /><searchLink fieldCode="AU" term="%22Luecken+MD%22">Luecken MD</searchLink>; Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany. malte.luecken@helmholtz-muenchen.de.<br /><searchLink fieldCode="AU" term="%22Eraslan+G%22">Eraslan G</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sikkema+L%22">Sikkema L</searchLink>; Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Waghray+A%22">Waghray A</searchLink>; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.; Departments of Internal Medicine and Pediatrics, Pulmonary and Critical Care Unit, Massachusetts General Hospital, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Heimberg+G%22">Heimberg G</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kobayashi+Y%22">Kobayashi Y</searchLink>; Department of Cell Biology, Duke University Medical School, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Vaishnav+ED%22">Vaishnav ED</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Subramanian+A%22">Subramanian A</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Smillie+C%22">Smillie C</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jagadeesh+KA%22">Jagadeesh KA</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Duong+ET%22">Duong ET</searchLink>; Division of Respiratory Medicine, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Fiskin+E%22">Fiskin E</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Torlai+Triglia+E%22">Torlai Triglia E</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ansari+M%22">Ansari M</searchLink>; Comprehensive Pneumology Center (CPC)/Institute of Lung Biology and Disease (ILBD), Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany.; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Cai+P%22">Cai P</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lin+B%22">Lin B</searchLink>; Departments of Internal Medicine and Pediatrics, Pulmonary and Critical Care Unit, Massachusetts General Hospital, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Buchanan+J%22">Buchanan J</searchLink>; Center for Epigenomics, University of California San Diego School of Medicine, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Shu+J%22">Shu J</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Haber+AL%22">Haber AL</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Environmental Health, Harvard T. 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Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chung+H%22">Chung H</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Montoro+DT%22">Montoro DT</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Adams+T%22">Adams T</searchLink>; Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Aliee+H%22">Aliee H</searchLink>; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Allon+SJ%22">Allon SJ</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering and Science & Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Andrusivova+Z%22">Andrusivova Z</searchLink>; SciLifeLab, Department of Gene Technology, KTH Royal Institute of Technology, Stockolm, Sweden.<br /><searchLink fieldCode="AU" term="%22Angelidis+I%22">Angelidis I</searchLink>; Comprehensive Pneumology Center (CPC)/Institute of Lung Biology and Disease (ILBD), Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ashenberg+O%22">Ashenberg O</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bassler+K%22">Bassler K</searchLink>; Department for Genomics & Immunoregulation, LIMES-Institute, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Bécavin+C%22">Bécavin C</searchLink>; Université Côte d'Azur, CNRS, IPMC, Sophia-Antipolis, France.<br /><searchLink fieldCode="AU" term="%22Benhar+I%22">Benhar I</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bergenstråhle+J%22">Bergenstråhle J</searchLink>; SciLifeLab, Department of Gene Technology, KTH Royal Institute of Technology, Stockolm, Sweden.<br /><searchLink fieldCode="AU" term="%22Bergenstråhle+L%22">Bergenstråhle L</searchLink>; SciLifeLab, Department of Gene Technology, KTH Royal Institute of Technology, Stockolm, Sweden.<br /><searchLink fieldCode="AU" term="%22Bolt+L%22">Bolt L</searchLink>; Wellcome Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Braun+E%22">Braun E</searchLink>; Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Bui+LT%22">Bui LT</searchLink>; Translational Genomics Research Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Callori+S%22">Callori S</searchLink>; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.; Bioinformatics Program, Boston University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chaffin+M%22">Chaffin M</searchLink>; Precision Cardiology Laboratory, The Broad Institute, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chichelnitskiy+E%22">Chichelnitskiy E</searchLink>; Institute of Transplant Immunology, Hannover Medical School, MHH, Hannover, Germany.; German Center for Infectious Diseases (DZIF), Braunschweig, Germany.<br /><searchLink fieldCode="AU" term="%22Chiou+J%22">Chiou J</searchLink>; Biomedical Sciences Graduate Program, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Conlon+TM%22">Conlon TM</searchLink>; Comprehensive Pneumology Center (CPC)/Institute of Lung Biology and Disease (ILBD), Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Cuoco+MS%22">Cuoco MS</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cuomo+ASE%22">Cuomo ASE</searchLink>; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Deprez+M%22">Deprez M</searchLink>; Université Côte d'Azur, CNRS, IPMC, Sophia-Antipolis, France.<br /><searchLink fieldCode="AU" term="%22Duclos+G%22">Duclos G</searchLink>; Boston University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fine+D%22">Fine D</searchLink>; Boston University Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fischer+DS%22">Fischer DS</searchLink>; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.<br /><searchLink fieldCode="AU" term="%22Ghazanfar+S%22">Ghazanfar S</searchLink>; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Gillich+A%22">Gillich A</searchLink>; Department of Biochemistry and Wall Center for Pulmonary Vascular Disease, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Giotti+B%22">Giotti B</searchLink>; Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Gould+J%22">Gould J</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Guo+M%22">Guo M</searchLink>; Divisions of Pulmonary Biology; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Gutierrez+AJ%22">Gutierrez AJ</searchLink>; Translational Genomics Research Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Habermann+AC%22">Habermann AC</searchLink>; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Harvey+T%22">Harvey T</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22He+P%22">He P</searchLink>; Wellcome Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Hou+X%22">Hou X</searchLink>; Center for Epigenomics, University of California-San Diego School of Medicine, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California-San Diego School of Medicine, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hu+L%22">Hu L</searchLink>; Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Hu+Y%22">Hu Y</searchLink>; Division of Pulmonary Sciences and Critical Care Medicine, School of Medicine, University of Colorado, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Jaiswal+A%22">Jaiswal A</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ji+L%22">Ji L</searchLink>; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, SAR, China.<br /><searchLink fieldCode="AU" term="%22Jiang+P%22">Jiang P</searchLink>; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, SAR, China.<br /><searchLink fieldCode="AU" term="%22Kapellos+TS%22">Kapellos TS</searchLink>; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Kuo+CS%22">Kuo CS</searchLink>; Division of Pulmonary Medicine, Department of Pediatrics, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Larsson+L%22">Larsson L</searchLink>; SciLifeLab, Department of Gene Technology, KTH Royal Institute of Technology, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Leney-Greene+MA%22">Leney-Greene MA</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lim+K%22">Lim K</searchLink>; Gurdon Institute, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Litviňuková+M%22">Litviňuková M</searchLink>; Cellular Genetics Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Ludwig+LS%22">Ludwig LS</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lukassen+S%22">Lukassen S</searchLink>; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; Berlin Institute of Health (BIH), Center for Digital Health, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Luo+W%22">Luo W</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Maatz+H%22">Maatz H</searchLink>; Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Madissoon+E%22">Madissoon E</searchLink>; European Molecular Biology Laboratory-European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, UK.; Wellcome Sanger Institute, Cellular Genetics Programme Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Mamanova+L%22">Mamanova L</searchLink>; Wellcome Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Manakongtreecheep+K%22">Manakongtreecheep K</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Charlestown, MA, USA.<br /><searchLink fieldCode="AU" term="%22Leroy+S%22">Leroy S</searchLink>; Pulmonology Department, Université Côte d'Azur, CHU Nice, Nice, France.; CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Sophia-Antipolis, France.<br /><searchLink fieldCode="AU" term="%22Mayr+CH%22">Mayr CH</searchLink>; Helmholtz Zentrum München, Institute of Lung Biology and Disease, Group Systems Medicine of Chronic Lung Disease, Member of the German Center for Lung Research (DZL), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Mbano+IM%22">Mbano IM</searchLink>; Africa Health Research Institute, Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of Kwazulu Natal, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22McAdams+AM%22">McAdams AM</searchLink>; Department of Ophthalmology, Harvard Medical School and Massachusetts Eye and Ear, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nabhan+AN%22">Nabhan AN</searchLink>; Department of Biochemistry and Wall Center for Pulmonary Vascular Disease, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nyquist+SK%22">Nyquist SK</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Computational and Systems Biology, CSAIL, Institute for Medical Engineering and Science & Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Penland+L%22">Penland L</searchLink>; Department of Biochemistry and Wall Center for Pulmonary Vascular Disease, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Poirion+OB%22">Poirion OB</searchLink>; Center for Epigenomics, University of California-San Diego School of Medicine, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California-San Diego School of Medicine, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Poli+S%22">Poli S</searchLink>; Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Qi+C%22">Qi C</searchLink>; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Queen+R%22">Queen R</searchLink>; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, International Centre for Life, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Reichart+D%22">Reichart D</searchLink>; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Department of Cardiology, University Heart & Vascular Center, University of Hamburg, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Rosas+I%22">Rosas I</searchLink>; Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Schupp+JC%22">Schupp JC</searchLink>; Section of Pulmonary, Critical Care, and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Shea+CV%22">Shea CV</searchLink>; Division of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Shi+X%22">Shi X</searchLink>; Division of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.; Bioinformatics Program, Boston University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sinha+R%22">Sinha R</searchLink>; Institute for Stem Cell Biology and Regenerative Medicine, Stanford Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sit+RV%22">Sit RV</searchLink>; Department of Biochemistry and Wall Center for Pulmonary Vascular Disease, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Slowikowski+K%22">Slowikowski K</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Charlestown, MA, USA.<br /><searchLink fieldCode="AU" term="%22Slyper+M%22">Slyper M</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Smith+NP%22">Smith NP</searchLink>; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sountoulidis+A%22">Sountoulidis A</searchLink>; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Strunz+M%22">Strunz M</searchLink>; Comprehensive Pneumology Center (CPC) and Institute of Lung Biology and Disease (ILBD), Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Sullivan+TB%22">Sullivan TB</searchLink>; Lahey Hospital & Medical Center, Burlington, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sun+D%22">Sun D</searchLink>; Gurdon Institute, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Talavera-López+C%22">Talavera-López C</searchLink>; Cellular Genetics Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Tan+P%22">Tan P</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tantivit+J%22">Tantivit J</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Charlestown, MA, USA.<br /><searchLink fieldCode="AU" term="%22Travaglini+KJ%22">Travaglini KJ</searchLink>; Department of Biochemistry and Wall Center for Pulmonary Vascular Disease, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tucker+NR%22">Tucker NR</searchLink>; Precision Cardiology Laboratory, The Broad Institute, Cambridge, MA, USA.; Masonic Medical Research Institute, Utica, NY, USA.<br /><searchLink fieldCode="AU" term="%22Vernon+KA%22">Vernon KA</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wadsworth+MH%22">Wadsworth MH</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering and Science, Department of Chemistry & Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Waldman+J%22">Waldman J</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Xu+K%22">Xu K</searchLink>; Division of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yan+W%22">Yan W</searchLink>; Center for Brain Science, Harvard University, Cambridge, MA, USA.; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+W%22">Zhao W</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ziegler+CGK%22">Ziegler CGK</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Harvard-MIT Health Sciences and Technology, Institute for Medical Engineering and Science, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
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  Data: <searchLink fieldCode="CA" term="%22NHLBI+LungMap+Consortium%22">NHLBI LungMap Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22Human+Cell+Atlas+Lung+Biological+Network%22">Human Cell Atlas Lung Biological Network</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229502015%22">Nature medicine</searchLink> [Nat Med] 2021 Mar; Vol. 27 (3), pp. 546-559. <i>Date of Electronic Publication: </i>2021 Mar 02.
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  Data: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Company%22">Nature Publishing Company </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502015 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1546-170X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210788956%22">10788956 </searchLink><i>NLM ISO Abbreviation: </i>Nat Med <i>Subsets: </i>MEDLINE
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      – TitleFull: Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
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          Name:
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            NameFull: Strunz M
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            – D: 01
              M: 03
              Text: 2021 Mar
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-electronic
              Value: 1546-170X
          Numbering:
            – Type: volume
              Value: 27
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Nature medicine
              Type: main
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