Expanded high-throughput screening and chemotype-enrichment analysis of the phase II: e1k ToxCast library for human sodium-iodide symporter (NIS) inhibition.
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| Title: | Expanded high-throughput screening and chemotype-enrichment analysis of the phase II: e1k ToxCast library for human sodium-iodide symporter (NIS) inhibition. |
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| Authors: | Wang J; Neurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, Center for Public Health & Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA.; Oak Ridge Institute for Science and Education, U.S. Department of Energy, Oak Ridge, TN, 37831, USA., Richard AM; Computational Chemistry & Cheminformatics Branch, Center for Computational Toxicology & Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA., Murr AS; Neurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, Center for Public Health & Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA., Buckalew AR; Neurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, Center for Public Health & Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA., Lougee RR; Oak Ridge Institute for Science and Education, U.S. Department of Energy, Oak Ridge, TN, 37831, USA.; Computational Chemistry & Cheminformatics Branch, Center for Computational Toxicology & Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA., Shobair M; Computational Chemistry & Cheminformatics Branch, Center for Computational Toxicology & Exposure, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA., Hallinger DR; Neurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, Center for Public Health & Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA., Laws SC; Neurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, Center for Public Health & Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA., Stoker TE; Neurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, Center for Public Health & Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, 27711, USA. stoker.tammy@epa.gov. |
| Source: | Archives of toxicology [Arch Toxicol] 2021 May; Vol. 95 (5), pp. 1723-1737. Date of Electronic Publication: 2021 Mar 03. |
| Publication Type: | Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-0738 |
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| DOI: | 10.1007/s00204-021-03006-2 |
