Identification of Reduced Host Transcriptomic Signatures for Tuberculosis Disease and Digital PCR-Based Validation and Quantification.

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Title: Identification of Reduced Host Transcriptomic Signatures for Tuberculosis Disease and Digital PCR-Based Validation and Quantification.
Authors: Gliddon HD; Section of Paediatrics, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.; National Public Health Speciality Training Programme, South West, United Kingdom., Kaforou M; Section of Paediatrics, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom., Alikian M; Imperial Molecular Pathology, Imperial Healthcare Trust, Hammersmith Hospital, London, United Kingdom.; Centre for Haematology, Faculty of Medicine, Imperial College London, London, United Kingdom., Habgood-Coote D; Section of Paediatrics, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom., Zhou C; Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD, Australia., Oni T; School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Anderson ST; Brighton and Sussex Medical School, Brighton, United Kingdom.; Brighton and Malawi Liverpool Wellcome Trust Unit, Blantyre, Malawi., Brent AJ; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford University Hospitals National Health Service (NHS) Foundation Trust, Oxford, United Kingdom., Crampin AC; Malawi Epidemiology and Intervention Research Unit, Chilumba, Malawi.; London School of Hygiene & Tropical Medicine, London, United Kingdom.; Karonga Prevention Study, Chilumba, Malawi., Eley B; Paediatric Infectious Diseases Unit, Red Cross War Memorial Children's Hospital, Cape Town, South Africa.; Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa., Heyderman R; Division of Infection and Immunity, Faculty of Medical Sciences, University College London, London, United Kingdom., Kern F; Brighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom.; Brighton and Sussex University Hospitals National Health Service (NHS) Trust, Brighton, United Kingdom., Langford PR; Section of Paediatrics, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom., Ottenhoff THM; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands., Hibberd ML; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., French N; Tropical and Infectious Disease Unit, Royal Liverpool and Broadgreen University Hospitals National Health Service (NHS) Trust, Liverpool, United Kingdom.; Centre for Global Vaccine Research, Institute of Infection & Global Health, University of Liverpool, Liverpool, United Kingdom., Wright VJ; Section of Paediatrics, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom., Dockrell HM; Department of Immunology and Infection, and Tuberculosis (TB) Centre, London School of Hygiene and Tropical Medicine, London, United Kingdom., Coin LJ; Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD, Australia., Wilkinson RJ; The Francis Crick Institute, London, United Kingdom.; Department of Medicine, Imperial College London, London, United Kingdom.; Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa., Levin M; Section of Paediatrics, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.
Source: Frontiers in immunology [Front Immunol] 2021 Mar 02; Vol. 12, pp. 637164. Date of Electronic Publication: 2021 Mar 02 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2021.637164