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Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders.

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Title: Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders.
Authors: Nabais MF; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.; University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK., Laws SM; School of Medical and Health Sciences, Edith Cowan University, 270 Joondalup Dr, Joondalup, WA, 6027, Australia., Lin T; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia., Vallerga CL; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.; Department of Internal Medicine, Erasmus MC, University Medical Center, 3015GD, Rotterdam, The Netherlands., Armstrong NJ; Murdoch University, 90 South St, Murdoch, WA, 6150, Australia., Blair IP; Australian Centre for Precision Health, University of South Australia Cancer Research Institute, School of Health Sciences, University of South Australia, Adelaide, SA, 5001, Australia., Kwok JB; Brain and Mind Centre, Sydney Medical School, The University of Sydney, Sydney, Australia., Mather KA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, 2031, Australia.; Neuroscience Research Australia Institute, Randwick, NSW, 2031, Australia., Mellick GD; Griffith Institute for Drug Discovery (GRIDD), Griffith University, Brisbane, Australia., Sachdev PS; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, 2031, Australia.; Neuropsychiatric Institute, The Prince of Wales Hospital, UNSW, Randwick, NSW, 2031, Australia., Wallace L; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia., Henders AK; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia., Zwamborn RAJ; Department of Neurology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., Hop PJ; Department of Neurology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., Lunnon K; University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK., Pishva E; University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK., Roubroeks JAY; University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK., Soininen H; Institute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland., Tsolaki M; 1st Department of Neurology, Memory and Dementia Unit, Aristotle University of Thessaloniki, Thessaloniki, Greece., Mecocci P; Department of Medicine, Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy., Lovestone S; Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK., Kłoszewska I; Medical University of Lodz, Lodz, Poland., Vellas B; INSERM U 558, University of Toulouse, Toulouse, France., Furlong S; Centre for Motor Neuron Disease Research, Macquarie University, Sydney, NSW, 2109, Australia., Garton FC; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia., Henderson RD; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072, Australia.; Centre for Clinical Research, The University of Queensland, Brisbane, QLD, 4019, Australia.; Department of Neurology, Royal Brisbane and Women's Hospital, Brisbane, QLD, 4029, Australia., Mathers S; Calvary Health Care Bethlehem, Parkdale, VIC, 3195, Australia., McCombe PA; Centre for Clinical Research, The University of Queensland, Brisbane, QLD, 4019, Australia.; Department of Neurology, Royal Brisbane and Women's Hospital, Brisbane, QLD, 4029, Australia., Needham M; Fiona Stanley Hospital, Perth, WA, 6150, Australia.; Notre Dame University, Fremantle, WA, 6160, Australia.; Institute for Immunology and Infectious Diseases, Murdoch University, Perth, WA, 6150, Australia., Ngo ST; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072, Australia.; Centre for Clinical Research, The University of Queensland, Brisbane, QLD, 4019, Australia.; The Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, 4072, Australia., Nicholson G; ANZAC Research Institute, Concord Repatriation General Hospital, Sydney, NSW, 2139, Australia., Pamphlett R; Discipline of Pathology and Department of Neuropathology, Brain and Mind Centre, The University of Sydney, Sydney, NSW, 2050, Australia., Rowe DB; Centre for Motor Neuron Disease Research, Macquarie University, Sydney, NSW, 2109, Australia., Steyn FJ; Department of Neurology, Royal Brisbane and Women's Hospital, Brisbane, QLD, 4029, Australia.; School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, 4072, Australia., Williams KL; Centre for Motor Neuron Disease Research, Macquarie University, Sydney, NSW, 2109, Australia., Anderson TJ; New Zealand Brain Research Institute, Christchurch, New Zealand.; Department of Medicine, University of Otago, Christchurch, New Zealand., Bentley SR; Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Australia., Dalrymple-Alford J; New Zealand Brain Research Institute, Christchurch, New Zealand.; School of Psychology, Speech and Hearing, University of Canterbury, Christchurch, New Zealand., Fowder J; Griffith Institute for Drug Discovery (GRIDD), Griffith University, Brisbane, Australia., Gratten J; Mater Research, Translational Research Institute, Brisbane, Australia.; Mater Research Institute, The University of Queensland, Brisbane, Australia., Halliday G; Brain and Mind Research Centre, Sydney Medical School, The University of Sydney, Sydney, Australia., Hickie IB; Brain and Mind Research Centre, Sydney Medical School, The University of Sydney, Sydney, Australia., Kennedy M; Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand., Lewis SJG; Brain and Mind Research Centre, Sydney Medical School, The University of Sydney, Sydney, Australia., Montgomery GW; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia., Pearson J; Department of Pathology, University of Otago, Christchurch, New Zealand., Pitcher TL; New Zealand Brain Research Institute, Christchurch, New Zealand.; Department of Medicine, University of Otago, Christchurch, New Zealand., Silburn P; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072, Australia., Zhang F; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia., Visscher PM; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia., Yang J; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.; School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China., Stevenson AJ; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Hillary RF; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Marioni RE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Harris SE; Department of Psychology, Lothian Birth Cohorts group, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK., Deary IJ; Department of Psychology, Lothian Birth Cohorts group, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK., Jones AR; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, SE5 9RX, UK., Shatunov A; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, SE5 9RX, UK., Iacoangeli A; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, SE5 9RX, UK., van Rheenen W; Department of Neurology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., van den Berg LH; Department of Neurology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., Shaw PJ; SITraN, University of Sheffield, Sheffield, UK., Shaw CE; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, SE5 9RX, UK., Morrison KE; Queen's University Belfast, Belfast, Northern Ireland, UK., Al-Chalabi A; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, SE5 9RX, UK.; King's College Hospital, London, SE5 9RS, UK., Veldink JH; Department of Neurology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., Hannon E; University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK., Mill J; University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK.; Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 8AF, UK., Wray NR; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072, Australia., McRae AF; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia. a.mcrae@uq.edu.au.
Corporate Authors: Australian Imaging Biomarkers and Lifestyle study, Alzheimer’s Disease Neuroimaging Initiative
Source: Genome biology [Genome Biol] 2021 Mar 26; Vol. 22 (1), pp. 90. Date of Electronic Publication: 2021 Mar 26.
Publication Type: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
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  Data: Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders.
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  Data: <searchLink fieldCode="AU" term="%22Nabais+MF%22">Nabais MF</searchLink>; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.; University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK.<br /><searchLink fieldCode="AU" term="%22Laws+SM%22">Laws SM</searchLink>; School of Medical and Health Sciences, Edith Cowan University, 270 Joondalup Dr, Joondalup, WA, 6027, Australia.<br /><searchLink fieldCode="AU" term="%22Lin+T%22">Lin T</searchLink>; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Vallerga+CL%22">Vallerga CL</searchLink>; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.; Department of Internal Medicine, Erasmus MC, University Medical Center, 3015GD, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Armstrong+NJ%22">Armstrong NJ</searchLink>; Murdoch University, 90 South St, Murdoch, WA, 6150, Australia.<br /><searchLink fieldCode="AU" term="%22Blair+IP%22">Blair IP</searchLink>; Australian Centre for Precision Health, University of South Australia Cancer Research Institute, School of Health Sciences, University of South Australia, Adelaide, SA, 5001, Australia.<br /><searchLink fieldCode="AU" term="%22Kwok+JB%22">Kwok JB</searchLink>; Brain and Mind Centre, Sydney Medical School, The University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Mather+KA%22">Mather KA</searchLink>; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, 2031, Australia.; Neuroscience Research Australia Institute, Randwick, NSW, 2031, Australia.<br /><searchLink fieldCode="AU" term="%22Mellick+GD%22">Mellick GD</searchLink>; Griffith Institute for Drug Discovery (GRIDD), Griffith University, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Sachdev+PS%22">Sachdev PS</searchLink>; 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Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kłoszewska+I%22">Kłoszewska I</searchLink>; Medical University of Lodz, Lodz, Poland.<br /><searchLink fieldCode="AU" term="%22Vellas+B%22">Vellas B</searchLink>; INSERM U 558, University of Toulouse, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Furlong+S%22">Furlong S</searchLink>; Centre for Motor Neuron Disease Research, Macquarie University, Sydney, NSW, 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Garton+FC%22">Garton FC</searchLink>; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Henderson+RD%22">Henderson RD</searchLink>; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072, Australia.; Centre for Clinical Research, The University of Queensland, Brisbane, QLD, 4019, Australia.; Department of Neurology, Royal Brisbane and Women's Hospital, Brisbane, QLD, 4029, Australia.<br /><searchLink fieldCode="AU" term="%22Mathers+S%22">Mathers S</searchLink>; Calvary Health Care Bethlehem, Parkdale, VIC, 3195, Australia.<br /><searchLink fieldCode="AU" term="%22McCombe+PA%22">McCombe PA</searchLink>; Centre for Clinical Research, The University of Queensland, Brisbane, QLD, 4019, Australia.; Department of Neurology, Royal Brisbane and Women's Hospital, Brisbane, QLD, 4029, Australia.<br /><searchLink fieldCode="AU" term="%22Needham+M%22">Needham M</searchLink>; Fiona Stanley Hospital, Perth, WA, 6150, Australia.; Notre Dame University, Fremantle, WA, 6160, Australia.; Institute for Immunology and Infectious Diseases, Murdoch University, Perth, WA, 6150, Australia.<br /><searchLink fieldCode="AU" term="%22Ngo+ST%22">Ngo ST</searchLink>; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072, Australia.; Centre for Clinical Research, The University of Queensland, Brisbane, QLD, 4019, Australia.; The Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Nicholson+G%22">Nicholson G</searchLink>; ANZAC Research Institute, Concord Repatriation General Hospital, Sydney, NSW, 2139, Australia.<br /><searchLink fieldCode="AU" term="%22Pamphlett+R%22">Pamphlett R</searchLink>; Discipline of Pathology and Department of Neuropathology, Brain and Mind Centre, The University of Sydney, Sydney, NSW, 2050, Australia.<br /><searchLink fieldCode="AU" term="%22Rowe+DB%22">Rowe DB</searchLink>; Centre for Motor Neuron Disease Research, Macquarie University, Sydney, NSW, 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Steyn+FJ%22">Steyn FJ</searchLink>; Department of Neurology, Royal Brisbane and Women's Hospital, Brisbane, QLD, 4029, Australia.; School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Williams+KL%22">Williams KL</searchLink>; Centre for Motor Neuron Disease Research, Macquarie University, Sydney, NSW, 2109, Australia.<br /><searchLink fieldCode="AU" term="%22Anderson+TJ%22">Anderson TJ</searchLink>; 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University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Barrack Road, Exeter, EX2 5DW, UK.; Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 8AF, UK.<br /><searchLink fieldCode="AU" term="%22Wray+NR%22">Wray NR</searchLink>; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072, Australia.<br /><searchLink fieldCode="AU" term="%22McRae+AF%22">McRae AF</searchLink>; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia. a.mcrae@uq.edu.au.
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  Data: <searchLink fieldCode="JN" term="%22100960660%22">Genome biology</searchLink> [Genome Biol] 2021 Mar 26; Vol. 22 (1), pp. 90. <i>Date of Electronic Publication: </i>2021 Mar 26.
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            NameFull: Al-Chalabi A
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    IsPartOfRelationships:
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          Dates:
            – D: 26
              M: 03
              Text: 2021 Mar 26
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-electronic
              Value: 1474-760X
          Numbering:
            – Type: volume
              Value: 22
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Genome biology
              Type: main
ResultId 1