| Authors: |
Delorey TM; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ziegler CGK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Health Sciences & Technology, Harvard Medical School and Massachusetts Institute of Technology, Boston, MA, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Harvard Graduate Program in Biophysics, Harvard University, Cambridge, MA, USA., Heimberg G; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Normand R; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Massachusetts Institute of Technology, Cambridge, MA, USA., Yang Y; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Segerstolpe Å; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Abbondanza D; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Fleming SJ; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Precision Cardiology Laboratory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Subramanian A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Montoro DT; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Jagadeesh KA; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Dey KK; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA, USA., Sen P; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Slyper M; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pita-Juárez YH; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School Initiative for RNA Medicine, Boston, MA, USA.; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA., Phillips D; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Biermann J; Department of Medicine, Division of Hematology/Oncology, Columbia University Irving Medical Center, New York, NY, USA.; Columbia Center for Translational Immunology, New York, NY, USA., Bloom-Ackermann Z; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Barkas N; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ganna A; Institute for Molecular Medicine Finland, Helsinki, Finland.; Analytical & Translational Genetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Gomez J; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Melms JC; Department of Medicine, Division of Hematology/Oncology, Columbia University Irving Medical Center, New York, NY, USA.; Columbia Center for Translational Immunology, New York, NY, USA., Katsyv I; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Normandin E; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA., Naderi P; Harvard Medical School, Boston, MA, USA.; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School Initiative for RNA Medicine, Boston, MA, USA., Popov YV; Harvard Medical School, Boston, MA, USA.; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Raju SS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA., Niezen S; Harvard Medical School, Boston, MA, USA.; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Tsai LT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Boston Nutrition and Obesity Research Center Functional Genomics and Bioinformatics Core Boston, Boston, MA, USA., Siddle KJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA., Sud M; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tran VM; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Vellarikkal SK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Divisions of Cardiovascular Medicine and Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Wang Y; Department of Medicine, Division of Hematology/Oncology, Columbia University Irving Medical Center, New York, NY, USA.; Columbia Center for Translational Immunology, New York, NY, USA., Amir-Zilberstein L; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Atri DS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Divisions of Cardiovascular Medicine and Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Beechem J; NanoString Technologies Inc, Seattle, WA, USA., Brook OR; Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Chen J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Divakar P; NanoString Technologies Inc, Seattle, WA, USA., Dorceus P; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics and BASE Initiative, Stanford University School of Medicine, Stanford, CA, USA., Essene A; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Boston Nutrition and Obesity Research Center Functional Genomics and Bioinformatics Core Boston, Boston, MA, USA., Fitzgerald DM; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Fropf R; NanoString Technologies Inc, Seattle, WA, USA., Gazal S; Center for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Gould J; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Grzyb J; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Harvey T; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hecht J; Harvard Medical School, Boston, MA, USA.; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Hether T; NanoString Technologies Inc, Seattle, WA, USA., Jané-Valbuena J; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Leney-Greene M; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ma H; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., McCabe C; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., McLoughlin DE; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Miller EM; NanoString Technologies Inc, Seattle, WA, USA., Muus C; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA., Niemi M; Institute for Molecular Medicine Finland, Helsinki, Finland., Padera R; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA., Pan L; NanoString Technologies Inc, Seattle, WA, USA., Pant D; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Boston Nutrition and Obesity Research Center Functional Genomics and Bioinformatics Core Boston, Boston, MA, USA., Pe'er C; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pfiffner-Borges J; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pinto CJ; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Plaisted J; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Reeves J; NanoString Technologies Inc, Seattle, WA, USA., Ross M; NanoString Technologies Inc, Seattle, WA, USA., Rudy M; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Rueckert EH; NanoString Technologies Inc, Seattle, WA, USA., Siciliano M; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Sturm A; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Todres E; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Waghray A; Harvard Stem Cell Institute, Cambridge, MA, USA.; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA., Warren S; NanoString Technologies Inc, Seattle, WA, USA., Zhang S; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Zollinger DR; NanoString Technologies Inc, Seattle, WA, USA., Cosimi L; Infectious Diseases Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Gupta RM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Divisions of Cardiovascular Medicine and Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Hacohen N; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Hibshoosh H; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA., Hide W; Harvard Medical School, Boston, MA, USA.; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School Initiative for RNA Medicine, Boston, MA, USA.; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA., Price AL; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA, USA., Rajagopal J; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Tata PR; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA., Riedel S; Harvard Medical School, Boston, MA, USA.; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Szabo G; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Tickle TL; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ellinor PT; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hung D; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA, USA., Sabeti PC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.; Massachusetts Consortium on Pathogen Readiness, Boston, MA, USA., Novak R; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Rogers R; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Massachusetts General Hospital, Boston, MA, USA., Ingber DE; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.; Vascular Biology Program and Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Jiang ZG; Harvard Medical School, Boston, MA, USA.; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Juric D; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Babadi M; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Precision Cardiology Laboratory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Farhi SL; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Izar B; Department of Medicine, Division of Hematology/Oncology, Columbia University Irving Medical Center, New York, NY, USA.; Columbia Center for Translational Immunology, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, USA.; Program for Mathematical Genomics, Columbia University Irving Medical Center, New York, NY, USA., Stone JR; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Vlachos IS; Broad Institute of MIT and Harvard, Cambridge, MA, USA. ivlachos@bidmc.harvard.edu.; Harvard Medical School, Boston, MA, USA. ivlachos@bidmc.harvard.edu.; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA. ivlachos@bidmc.harvard.edu.; Harvard Medical School Initiative for RNA Medicine, Boston, MA, USA. ivlachos@bidmc.harvard.edu.; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA. ivlachos@bidmc.harvard.edu., Solomon IH; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Ashenberg O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Porter CBM; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Li B; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Shalek AK; Broad Institute of MIT and Harvard, Cambridge, MA, USA. shalek@mit.edu.; Program in Health Sciences & Technology, Harvard Medical School and Massachusetts Institute of Technology, Boston, MA, USA. shalek@mit.edu.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA. shalek@mit.edu.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. shalek@mit.edu.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA. shalek@mit.edu.; Harvard Graduate Program in Biophysics, Harvard University, Cambridge, MA, USA. shalek@mit.edu.; Harvard Medical School, Boston, MA, USA. shalek@mit.edu.; Harvard Stem Cell Institute, Cambridge, MA, USA. shalek@mit.edu.; Program in Computational & Systems Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. shalek@mit.edu.; Program in Immunology, Harvard Medical School, Boston, MA, USA. shalek@mit.edu.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA. shalek@mit.edu., Villani AC; Broad Institute of MIT and Harvard, Cambridge, MA, USA. avillani@mgh.harvard.edu.; Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. avillani@mgh.harvard.edu.; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. avillani@mgh.harvard.edu.; Department of Medicine, Harvard Medical School, Boston, MA, USA. avillani@mgh.harvard.edu., Rozenblatt-Rosen O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA. orit.r.rosen@gmail.com.; Genentech, South San Francisco, CA, USA. orit.r.rosen@gmail.com., Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA. aviv.regev.sc@gmail.com.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. aviv.regev.sc@gmail.com.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. aviv.regev.sc@gmail.com.; Genentech, South San Francisco, CA, USA. aviv.regev.sc@gmail.com. |