High-frequency head impact causes chronic synaptic adaptation and long-term cognitive impairment in mice.

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Title: High-frequency head impact causes chronic synaptic adaptation and long-term cognitive impairment in mice.
Authors: Sloley SS; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Main BS; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Winston CN; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Harvey AC; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Kaganovich A; Laboratory of Neurogenetics, National Institute of Aging, Bethesda, MD, USA., Korthas HT; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Caccavano AP; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA., Zapple DN; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Wu JY; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Partridge JG; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA., Cookson MR; Laboratory of Neurogenetics, National Institute of Aging, Bethesda, MD, USA., Vicini S; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA., Burns MP; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA. mark.burns@georgetown.edu.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA. mark.burns@georgetown.edu.
Source: Nature communications [Nat Commun] 2021 May 10; Vol. 12 (1), pp. 2613. Date of Electronic Publication: 2021 May 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-021-22744-6