Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms.

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Title: Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms.
Authors: Shi Y; Department of Neurology, Washington University, St. Louis, MO 63110, USA., Andhey PS; Department of Pathology and Immunology, Washington University, St. Louis, MO 63110, USA., Ising C; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital of Bonn and German Center for Neurodegenerative Diseases (DZNE), Bonn 53127, Germany., Wang K; Department of Neurology, Washington University, St. Louis, MO 63110, USA., Snipes LL; Department of Pathology and Immunology, Washington University, St. Louis, MO 63110, USA., Boyer K; Department of Pathology and Immunology, Washington University, St. Louis, MO 63110, USA., Lawson S; Department of Pathology and Immunology, Washington University, St. Louis, MO 63110, USA., Yamada K; Department of Neuropathology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan., Qin W; Department of Psychiatry, Washington University, St. Louis, MO 63110, USA., Manis M; Department of Neurology, Washington University, St. Louis, MO 63110, USA., Serrano JR; Department of Neurology, Washington University, St. Louis, MO 63110, USA., Benitez BA; Department of Psychiatry, Washington University, St. Louis, MO 63110, USA., Schmidt RE; Department of Pathology and Immunology, Washington University, St. Louis, MO 63110, USA., Artyomov M; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital of Bonn and German Center for Neurodegenerative Diseases (DZNE), Bonn 53127, Germany., Ulrich JD; Department of Neurology, Washington University, St. Louis, MO 63110, USA. Electronic address: ulrichj@wustl.edu., Holtzman DM; Department of Neurology, Washington University, St. Louis, MO 63110, USA. Electronic address: holtzman@wustl.edu.
Source: Neuron [Neuron] 2021 Aug 04; Vol. 109 (15), pp. 2413-2426.e7. Date of Electronic Publication: 2021 Jun 21.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-4199
DOI:10.1016/j.neuron.2021.05.034