View in EDS HTML Full Text PDF Full Text

Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity.

Saved in:
Bibliographic Details
Title: Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity.
Authors: Akbari P; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Gilani A; Department of Pharmacology and Medicine, New York Medical College School of Medicine, Valhalla, NY 10595, USA., Sosina O; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Kosmicki JA; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Khrimian L; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Fang YY; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Persaud T; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Garcia V; Department of Pharmacology and Medicine, New York Medical College School of Medicine, Valhalla, NY 10595, USA., Sun D; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Li A; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Mbatchou J; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Locke AE; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Benner C; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Verweij N; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Lin N; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Hossain S; Department of Pharmacology and Medicine, New York Medical College School of Medicine, Valhalla, NY 10595, USA., Agostinucci K; Department of Pharmacology and Medicine, New York Medical College School of Medicine, Valhalla, NY 10595, USA., Pascale JV; Department of Pharmacology and Medicine, New York Medical College School of Medicine, Valhalla, NY 10595, USA., Dirice E; Department of Pharmacology and Medicine, New York Medical College School of Medicine, Valhalla, NY 10595, USA., Dunn M; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Kraus WE; Division of Cardiology, Duke University Medical Center, Durham, NC 27710, USA.; Duke Center for Living, Duke University Medical Center, Durham, NC 27705, USA., Shah SH; Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27701, USA., Chen YI; Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation, and Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation, and Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Rader DJ; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA., Melander O; Department of Clinical Sciences Malmö, Lund University, 221 00 Malmö, Sweden.; Department of Emergency and Internal Medicine, Skåne University Hospital, 214 28, Malmö, Sweden., Still CD; Geisinger Obesity Institute, Geisinger Health System, Danville, PA 17882, USA., Mirshahi T; Geisinger Obesity Institute, Geisinger Health System, Danville, PA 17882, USA., Carey DJ; Geisinger Obesity Institute, Geisinger Health System, Danville, PA 17882, USA., Berumen-Campos J; Faculty of Medicine, National Autonomous University of Mexico, Copilco Universidad, Coyoacán, 4360 Ciudad de México, Mexico., Kuri-Morales P; Faculty of Medicine, National Autonomous University of Mexico, Copilco Universidad, Coyoacán, 4360 Ciudad de México, Mexico., Alegre-Díaz J; Faculty of Medicine, National Autonomous University of Mexico, Copilco Universidad, Coyoacán, 4360 Ciudad de México, Mexico., Torres JM; Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, England, UK., Emberson JR; Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, England, UK., Collins R; Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, England, UK., Balasubramanian S; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Hawes A; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Jones M; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Zambrowicz B; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Murphy AJ; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Paulding C; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Coppola G; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Overton JD; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Reid JG; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Shuldiner AR; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Cantor M; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Kang HM; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Abecasis GR; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Karalis K; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Economides AN; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Marchini J; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Yancopoulos GD; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Sleeman MW; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Altarejos J; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Della Gatta G; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Tapia-Conyer R; Faculty of Medicine, National Autonomous University of Mexico, Copilco Universidad, Coyoacán, 4360 Ciudad de México, Mexico., Schwartzman ML; Department of Pharmacology and Medicine, New York Medical College School of Medicine, Valhalla, NY 10595, USA., Baras A; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA. luca.lotta@regeneron.com aris.baras@regeneron.com., Ferreira MAR; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Lotta LA; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA. luca.lotta@regeneron.com aris.baras@regeneron.com.
Corporate Authors: Regeneron Genetics Center, DiscovEHR Collaboration
Source: Science (New York, N.Y.) [Science] 2021 Jul 02; Vol. 373 (6550).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
Description
ISSN:1095-9203
DOI:10.1126/science.abf8683