View in EDS HTML Full Text PDF Full Text

Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies.

Saved in:
Bibliographic Details
Title: Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies.
Authors: Armstrong LA; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom., Lange SM; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom., Dee Cesare V; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom., Matthews SP; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom., Nirujogi RS; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom., Cole I; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom., Hope A; Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom., Cunningham F; Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom., Toth R; MRC Reagents and Services, University of Dundee, Dundee, Scotland, United Kingdom., Mukherjee R; Institute of Biochemistry II, Goethe University Frankfurt Medical Faculty, University Hospital, Frankfurt am Main, Germany.; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt am Main, Germany., Bojkova D; Institute of Medical Virology, University Hospital Frankfurt, Frankfurt am Main, Germany., Gruber F; National Phenotypic Screening Centre, University of Dundee, Dundee, Scotland, United Kingdom., Gray D; Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom., Wyatt PG; Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom., Cinatl J; Institute of Medical Virology, University Hospital Frankfurt, Frankfurt am Main, Germany., Dikic I; Institute of Biochemistry II, Goethe University Frankfurt Medical Faculty, University Hospital, Frankfurt am Main, Germany.; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt am Main, Germany.; Max Planck Institute of Biophysics, Frankfurt am Main, Germany., Davies P; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom., Kulathu Y; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.
Source: PloS one [PLoS One] 2021 Jul 16; Vol. 16 (7), pp. e0253364. Date of Electronic Publication: 2021 Jul 16 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 34270554
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Armstrong+LA%22">Armstrong LA</searchLink>; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lange+SM%22">Lange SM</searchLink>; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dee+Cesare+V%22">Dee Cesare V</searchLink>; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Matthews+SP%22">Matthews SP</searchLink>; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nirujogi+RS%22">Nirujogi RS</searchLink>; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cole+I%22">Cole I</searchLink>; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hope+A%22">Hope A</searchLink>; Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cunningham+F%22">Cunningham F</searchLink>; Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Toth+R%22">Toth R</searchLink>; MRC Reagents and Services, University of Dundee, Dundee, Scotland, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mukherjee+R%22">Mukherjee R</searchLink>; Institute of Biochemistry II, Goethe University Frankfurt Medical Faculty, University Hospital, Frankfurt am Main, Germany.; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Bojkova+D%22">Bojkova D</searchLink>; Institute of Medical Virology, University Hospital Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Gruber+F%22">Gruber F</searchLink>; National Phenotypic Screening Centre, University of Dundee, Dundee, Scotland, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gray+D%22">Gray D</searchLink>; Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Wyatt+PG%22">Wyatt PG</searchLink>; Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cinatl+J%22">Cinatl J</searchLink>; Institute of Medical Virology, University Hospital Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Dikic+I%22">Dikic I</searchLink>; Institute of Biochemistry II, Goethe University Frankfurt Medical Faculty, University Hospital, Frankfurt am Main, Germany.; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt am Main, Germany.; Max Planck Institute of Biophysics, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Davies+P%22">Davies P</searchLink>; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kulathu+Y%22">Kulathu Y</searchLink>; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2021 Jul 16; Vol. 16 (7), pp. e0253364. <i>Date of Electronic Publication: </i>2021 Jul 16 (<i>Print Publication: </i>2021).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101285081 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-6203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219326203%22">19326203 </searchLink><i>NLM ISO Abbreviation: </i>PLoS One <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=34270554
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1371/journal.pone.0253364
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e0253364
    Titles:
      – TitleFull: Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Armstrong LA
      – PersonEntity:
          Name:
            NameFull: Lange SM
      – PersonEntity:
          Name:
            NameFull: Dee Cesare V
      – PersonEntity:
          Name:
            NameFull: Matthews SP
      – PersonEntity:
          Name:
            NameFull: Nirujogi RS
      – PersonEntity:
          Name:
            NameFull: Cole I
      – PersonEntity:
          Name:
            NameFull: Hope A
      – PersonEntity:
          Name:
            NameFull: Cunningham F
      – PersonEntity:
          Name:
            NameFull: Toth R
      – PersonEntity:
          Name:
            NameFull: Mukherjee R
      – PersonEntity:
          Name:
            NameFull: Bojkova D
      – PersonEntity:
          Name:
            NameFull: Gruber F
      – PersonEntity:
          Name:
            NameFull: Gray D
      – PersonEntity:
          Name:
            NameFull: Wyatt PG
      – PersonEntity:
          Name:
            NameFull: Cinatl J
      – PersonEntity:
          Name:
            NameFull: Dikic I
      – PersonEntity:
          Name:
            NameFull: Davies P
      – PersonEntity:
          Name:
            NameFull: Kulathu Y
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 16
              M: 07
              Text: 2021 Jul 16
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-electronic
              Value: 1932-6203
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: PloS one
              Type: main
ResultId 1