Inhibition of metabotropic glutamate receptor III facilitates sensitization to alkylating chemotherapeutics in glioblastoma.
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| Title: | Inhibition of metabotropic glutamate receptor III facilitates sensitization to alkylating chemotherapeutics in glioblastoma. |
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| Authors: | Maier JP; Microenvironment and Immunology Research Laboratory, Medical Center-University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center-University of Freiburg, Freiburg, Germany., Ravi VM; Microenvironment and Immunology Research Laboratory, Medical Center-University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center-University of Freiburg, Freiburg, Germany.; Neuroelectronic Systems, Medical Center-University of Freiburg, Freiburg, Germany., Kueckelhaus J; Microenvironment and Immunology Research Laboratory, Medical Center-University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center-University of Freiburg, Freiburg, Germany., Behringer SP; Microenvironment and Immunology Research Laboratory, Medical Center-University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center-University of Freiburg, Freiburg, Germany., Garrelfs N; Microenvironment and Immunology Research Laboratory, Medical Center-University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center-University of Freiburg, Freiburg, Germany., Will P; Microenvironment and Immunology Research Laboratory, Medical Center-University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center-University of Freiburg, Freiburg, Germany., Sun N; Research Unit Analytical Pathology, Helmholtz Zentrum München, Neuherberg, Germany., von Ehr J; Microenvironment and Immunology Research Laboratory, Medical Center-University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center-University of Freiburg, Freiburg, Germany., Goeldner JM; Microenvironment and Immunology Research Laboratory, Medical Center-University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center-University of Freiburg, Freiburg, Germany., Pfeifer D; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Hematology, Oncology and Stem Cell Transplantation, Medical Center-University of Freiburg, Freiburg, Germany., Follo M; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Medicine I, Medical Center-University of Freiburg, Freiburg, Germany., Hannibal L; Laboratory of Clinical Biochemistry and Metabolism, Department of General Pediatrics, Adolescent Medicine and Neonatology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany., Walch AK; Research Unit Analytical Pathology, Helmholtz Zentrum München, Neuherberg, Germany., Hofmann UG; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Neuroelectronic Systems, Medical Center-University of Freiburg, Freiburg, Germany., Beck J; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Heiland DH; Microenvironment and Immunology Research Laboratory, Medical Center-University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schnell O; Microenvironment and Immunology Research Laboratory, Medical Center-University of Freiburg, Freiburg, Germany.; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Translational NeuroOncology Research Group, Medical Center-University of Freiburg, Freiburg, Germany., Joseph K; Microenvironment and Immunology Research Laboratory, Medical Center-University of Freiburg, Freiburg, Germany. kevin.joseph@uniklinik-freiburg.de.; Department of Neurosurgery, Medical Center-University of Freiburg, Freiburg, Germany. kevin.joseph@uniklinik-freiburg.de.; Faculty of Medicine, University of Freiburg, Freiburg, Germany. kevin.joseph@uniklinik-freiburg.de.; Translational NeuroOncology Research Group, Medical Center-University of Freiburg, Freiburg, Germany. kevin.joseph@uniklinik-freiburg.de.; Neuroelectronic Systems, Medical Center-University of Freiburg, Freiburg, Germany. kevin.joseph@uniklinik-freiburg.de. |
| Source: | Cell death & disease [Cell Death Dis] 2021 Jul 21; Vol. 12 (8), pp. 723. Date of Electronic Publication: 2021 Jul 21. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-021-03937-9 |
