A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model.

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Title: A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model.
Authors: Peter AS; Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Roth E; Division of Molecular Immunology, Internal Medicine III, Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Schulz SR; Division of Molecular Immunology, Internal Medicine III, Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Fraedrich K; Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Steinmetz T; Division of Molecular Immunology, Internal Medicine III, Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Damm D; Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Hauke M; Division of Molecular Immunology, Internal Medicine III, Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Richel E; Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Mueller-Schmucker S; Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Habenicht K; Division of Genetics, Department Biology, Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Eberlein V; Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany., Issmail L; Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany., Uhlig N; Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany., Dolles S; Department of Chemistry & Pharmacy, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Grüner E; Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Peterhoff D; Institute of Medical Microbiology and Hygiene, Molecular Microbiology (Virology), University of Regensburg, Regensburg, Germany.; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany., Ciesek S; Institute of Medical Virology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt, Germany.; German Centre for Infection Research, External Partner Site, Frankfurt, Germany.; Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), Branch Translational Medicine and Pharmacology, Frankfurt, Germany., Hoffmann M; Infection Biology Unit, German Primate Center, Göttingen, Germany.; Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany., Pöhlmann S; Infection Biology Unit, German Primate Center, Göttingen, Germany.; Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany., McKay PF; Department of Infectious Diseases, Imperial College London, London, UK., Shattock RJ; Department of Infectious Diseases, Imperial College London, London, UK., Wölfel R; Bundeswehr Institute of Microbiology, Munich, Germany.; German Center for Infection Research, Partner Site Munich, Munich, Germany., Socher E; Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.; Division of Bioinformatics, Institute of Biochemistry, Emil-Fischer Center, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.; Institute of Anatomy, Functional and Clinical Anatomy, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Wagner R; Institute of Medical Microbiology and Hygiene, Molecular Microbiology (Virology), University of Regensburg, Regensburg, Germany., Eichler J; Department of Chemistry & Pharmacy, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Sticht H; Division of Bioinformatics, Institute of Biochemistry, Emil-Fischer Center, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Schuh W; Division of Molecular Immunology, Internal Medicine III, Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Neipel F; Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Ensser A; Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Mielenz D; Division of Molecular Immunology, Internal Medicine III, Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Tenbusch M; Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Winkler TH; Division of Genetics, Department Biology, Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Grunwald T; Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany., Überla K; Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Jäck HM; Division of Molecular Immunology, Internal Medicine III, Nikolaus-Fiebiger-Center of Molecular Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Source: European journal of immunology [Eur J Immunol] 2022 May; Vol. 52 (5), pp. 770-783. Date of Electronic Publication: 2021 Sep 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 1273201 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4141 (Electronic) Linking ISSN: 00142980 NLM ISO Abbreviation: Eur J Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1521-4141
DOI:10.1002/eji.202149374