Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination.
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| Title: | Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination. |
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| Authors: | Loyal L; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Braun J; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Henze L; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Kruse B; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Dingeldey M; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Reimer U; JPT Peptide Technologies GmbH, Berlin, Germany., Kern F; JPT Peptide Technologies GmbH, Berlin, Germany.; Department of Clinical and Experimental Medicine, Brighton and Sussex Medical School, Brighton, UK., Schwarz T; Institute of Virology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Mangold M; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Unger C; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Dörfler F; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany., Kadler S; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Medical Biotechnology, Institute for Biotechnology, Technische Universität Berlin, Berlin, Germany., Rosowski J; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Medical Biotechnology, Institute for Biotechnology, Technische Universität Berlin, Berlin, Germany., Gürcan K; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Medical Biotechnology, Institute for Biotechnology, Technische Universität Berlin, Berlin, Germany., Uyar-Aydin Z; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Medical Biotechnology, Institute for Biotechnology, Technische Universität Berlin, Berlin, Germany., Frentsch M; Department of Hematology, Oncology and Tumor Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Therapy-Induced Remodeling in Immuno-Oncology, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Kurth F; Department of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine, and Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Schnatbaum K; JPT Peptide Technologies GmbH, Berlin, Germany., Eckey M; JPT Peptide Technologies GmbH, Berlin, Germany., Hippenstiel S; Department of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany., Hocke A; Department of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany., Müller MA; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; Institute of Virology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; German Centre for Infection Research (DZIF), Partner Site Charité, Berlin, Germany., Sawitzki B; Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Miltenyi S; Miltenyi Biotec GmbH, Bergisch-Gladbach, Germany., Paul F; Experimental and Clinical Research Center, Max Delbrueck Center for Molecular Medicine, and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Clinical Neuroimmunology, NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, Berlin, Germany., Mall MA; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.; German Center for Lung Research, Associated Partner, Berlin, Germany., Wenschuh H; JPT Peptide Technologies GmbH, Berlin, Germany., Voigt S; Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany.; Institute for Virology, Universitätsklinikum Essen, Essen, Germany., Drosten C; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; Institute of Virology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; German Centre for Infection Research (DZIF), Partner Site Charité, Berlin, Germany., Lauster R; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Medical Biotechnology, Institute for Biotechnology, Technische Universität Berlin, Berlin, Germany., Lachman N; Institute for Transfusion Medicine, Tissue Typing Laboratory, Charité - Universitätsmedizin Berlin, Berlin, Germany., Sander LE; Department of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany., Corman VM; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; Institute of Virology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; German Centre for Infection Research (DZIF), Partner Site Charité, Berlin, Germany., Röhmel J; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany., Meyer-Arndt L; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; Experimental and Clinical Research Center, Max Delbrueck Center for Molecular Medicine, and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Clinical Neuroimmunology, NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Department of Neurology and Experimental Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Thiel A; Si-M/'Der Simulierte Mensch,' a Science Framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Giesecke-Thiel C; Max Planck Institute for Molecular Genetics, Berlin, Germany. |
| Source: | Science (New York, N.Y.) [Science] 2021 Oct 08; Vol. 374 (6564), pp. eabh1823. Date of Electronic Publication: 2021 Oct 08. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.abh1823 |
