A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia.

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Title: A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia.
Authors: Szabo A; NORMENT Center of Excellence (CoE), Institute of Clinical Medicine, University of Oslo, and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway. attila.szabo@medisin.uio.no.; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway. attila.szabo@medisin.uio.no.; KG Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo, Norway. attila.szabo@medisin.uio.no., Akkouh IA; NORMENT Center of Excellence (CoE), Institute of Clinical Medicine, University of Oslo, and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Vandenberghe M; NORMENT Center of Excellence (CoE), Institute of Clinical Medicine, University of Oslo, and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Osete JR; NORMENT Center of Excellence (CoE), Institute of Clinical Medicine, University of Oslo, and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Hughes T; NORMENT Center of Excellence (CoE), Institute of Clinical Medicine, University of Oslo, and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Heine V; Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit, Amsterdam, The Netherlands., Smeland OB; NORMENT Center of Excellence (CoE), Institute of Clinical Medicine, University of Oslo, and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Glover JC; Laboratory for Neural Development and Optical Recording (NDEVOR), Section for Physiology, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.; Norwegian Center for Stem Cell Research, Department of Immunology and Transfusion Medicine, Oslo University Hospital, Oslo, Norway., Andreassen OA; NORMENT Center of Excellence (CoE), Institute of Clinical Medicine, University of Oslo, and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; KG Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo, Norway., Djurovic S; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway. srdjan.djurovic@medisin.uio.no.; KG Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo, Norway. srdjan.djurovic@medisin.uio.no.; NORMENT CoE, Department of Clinical Science, University of Bergen, Bergen, Norway. srdjan.djurovic@medisin.uio.no.
Source: Translational psychiatry [Transl Psychiatry] 2021 Oct 29; Vol. 11 (1), pp. 554. Date of Electronic Publication: 2021 Oct 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2158-3188
DOI:10.1038/s41398-021-01681-4