Decrease of lysyl hydroxylase 2 activity causes abnormal collagen molecular phenotypes, defective mineralization and compromised mechanical properties of bone.

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Bibliographic Details
Title: Decrease of lysyl hydroxylase 2 activity causes abnormal collagen molecular phenotypes, defective mineralization and compromised mechanical properties of bone.
Authors: Saito T; Department of Oral Science, Graduate School of Medicine, Chiba University, Chiba, Japan., Terajima M; Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina at Chapel Hill, NC, USA., Taga Y; Nippi Research Institute of Biomatrix, Ibaraki 302-0017, Japan., Hayashi F; Department of Oral Science, Graduate School of Medicine, Chiba University, Chiba, Japan., Oshima S; Department of Oral Science, Graduate School of Medicine, Chiba University, Chiba, Japan., Kasamatsu A; Department of Dentistry and Oral-Maxillofacial Surgery, Chiba University Hospital, Chiba, Japan., Okubo Y; Department of Oral Science, Graduate School of Medicine, Chiba University, Chiba, Japan., Ito C; Department of Functional Anatomy, Reproductive Biology and Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan., Toshimori K; Department of Functional Anatomy, Reproductive Biology and Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan; Future Medicine Research Center, Chiba University, Chiba, Japan., Sunohara M; Department of Anatomy, School of Life Dentistry at Tokyo, Nippon Dental University, Tokyo, Japan., Tanzawa H; Department of Oral Science, Graduate School of Medicine, Chiba University, Chiba, Japan., Uzawa K; Department of Oral Science, Graduate School of Medicine, Chiba University, Chiba, Japan; Department of Dentistry and Oral-Maxillofacial Surgery, Chiba University Hospital, Chiba, Japan. Electronic address: uzawak@faculty.chiba-u.jp., Yamauchi M; Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina at Chapel Hill, NC, USA. Electronic address: mitsuo_yamauchi@unc.edu.
Source: Bone [Bone] 2022 Jan; Vol. 154, pp. 116242. Date of Electronic Publication: 2021 Oct 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8504048 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2763 (Electronic) Linking ISSN: 18732763 NLM ISO Abbreviation: Bone Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-2763
DOI:10.1016/j.bone.2021.116242