A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS.
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| Title: | A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS. |
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| Authors: | Katz JS; Forbes Norris MDA/ALS Research Center, California Pacific Medical Center, San Francisco, California, USA., Rothstein JD; Johns Hopkins Hospital, Baltimore, Maryland, USA., Cudkowicz ME; Sean M. Healey and AMG Center for ALS, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Genge A; Montreal Neurological Institute & Hospital, Montreal, QC, Canada., Oskarsson B; Mayo Clinic, Jacksonville, Florida, USA., Hains AB; Genentech, Inc., South San Francisco, California, USA., Chen C; Genentech, Inc., South San Francisco, California, USA., Galanter J; Genentech, Inc., South San Francisco, California, USA., Burgess BL; Genentech, Inc., South San Francisco, California, USA., Cho W; Genentech, Inc., South San Francisco, California, USA., Kerchner GA; F. Hoffmann-La Roche, Ltd., Basel, Switzerland., Yeh FL; Genentech, Inc., South San Francisco, California, USA., Ghosh AS; Genentech, Inc., South San Francisco, California, USA., Cheeti S; Genentech, Inc., South San Francisco, California, USA., Brooks L; Genentech, Inc., South San Francisco, California, USA., Honigberg L; Genentech, Inc., South San Francisco, California, USA., Couch JA; Genentech, Inc., South San Francisco, California, USA., Rothenberg ME; Genentech, Inc., South San Francisco, California, USA., Brunstein F; Genentech, Inc., South San Francisco, California, USA., Sharma KR; University of Miami Hospital (CRC), Miami, Florida, USA., van den Berg L; UMC Utrecht, Utrecht, The Netherlands., Berry JD; Neurological Clinical Research Institute, Boston, Massachusetts, USA., Glass JD; Emory University School of Medicine, Atlanta, Georgia, USA. |
| Source: | Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2022 Jan; Vol. 9 (1), pp. 50-66. Date of Electronic Publication: 2022 Jan 10. |
| Publication Type: | Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Periodicals, Inc on behalf of American Neurological Association Country of Publication: United States NLM ID: 101623278 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2328-9503 (Electronic) Linking ISSN: 23289503 NLM ISO Abbreviation: Ann Clin Transl Neurol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2328-9503 |
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| DOI: | 10.1002/acn3.51491 |
