Structural basis of BAK activation in mitochondrial apoptosis initiation.

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Title: Structural basis of BAK activation in mitochondrial apoptosis initiation.
Authors: Singh G; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA.; Integrative Biomedical Sciences Program, University of Tennessee Health Sciences Center, Memphis, TN, 38163, USA., Guibao CD; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA., Seetharaman J; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Aggarwal A; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA., Grace CR; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., McNamara DE; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA., Vaithiyalingam S; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Waddell MB; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Moldoveanu T; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA. tudor.moldoveanu@stjude.org.; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA. tudor.moldoveanu@stjude.org.
Source: Nature communications [Nat Commun] 2022 Jan 11; Vol. 13 (1), pp. 250. Date of Electronic Publication: 2022 Jan 11.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-021-27851-y