DAJIN enables multiplex genotyping to simultaneously validate intended and unintended target genome editing outcomes.

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Title: DAJIN enables multiplex genotyping to simultaneously validate intended and unintended target genome editing outcomes.
Authors: Kuno A; Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Ph.D Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, Tsukuba, Japan., Ikeda Y; Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan.; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Ayabe S; Experimental Animal Division, RIKEN BioResource Research Center, Tsukuba, Japan., Kato K; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Sakamoto K; Ph.D Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, Tsukuba, Japan.; Department of Computer Science, University of Tsukuba, Tsukuba, Japan., Suzuki SR; Ph.D Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, Tsukuba, Japan.; Bioinformatics Laboratory, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Morimoto K; Doctoral Program in Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan., Wakimoto A; Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Ph.D Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, Tsukuba, Japan., Mikami N; Ph.D Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, Tsukuba, Japan., Ishida M; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Iki N; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Hamada Y; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Takemura M; Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Daitoku Y; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Tanimoto Y; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Dinh TTH; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Murata K; Ph.D Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, Tsukuba, Japan.; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Hamada M; Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Muratani M; Department of Genome Biology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Yoshiki A; Experimental Animal Division, RIKEN BioResource Research Center, Tsukuba, Japan., Sugiyama F; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Takahashi S; Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Mizuno S; Laboratory Animal Resource Center, Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Source: PLoS biology [PLoS Biol] 2022 Jan 18; Vol. 20 (1), pp. e3001507. Date of Electronic Publication: 2022 Jan 18 (Print Publication: 2022).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1545-7885
DOI:10.1371/journal.pbio.3001507