Characterisation of age and polarity at onset in bipolar disorder.

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Title: Characterisation of age and polarity at onset in bipolar disorder.
Authors: Kalman JL; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Germany; Department of Psychiatry and Psychotherapy, University Hospital Munich, Germany; and International Max Planck Research School for Translational Psychiatry, Germany., Olde Loohuis LM; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, USA., Vreeker A; Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre-Sophia Children's Hospital, the Netherlands., McQuillin A; Division of Psychiatry, University College London, UK., Stahl EA; Division of Psychiatric Genomics, Mount Sinai School of Medicine, USA., Ruderfer D; Division of Genetic Medicine, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, USA; Department of Biomedical Informatics, Vanderbilt University Medical Center, USA; and Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, USA., Grigoroiu-Serbanescu M; Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, Romania., Panagiotaropoulou G; Department of Psychiatry and Psychotherapy, Charite - Universitätsmedizin, Germany., Ripke S; Analytic and Translational Genetics Unit, Massachusetts General Hospital, USA; and Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, USA., Bigdeli TB; Department of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, USA; and VA NY Harbor Healthcare System, USA., Stein F; Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Germany., Meller T; Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Germany; and Center for Mind, Brain and Behavior (CMBB), Germany., Meinert S; Institute for Translational Psychiatry, Westfälische Wilhelms-Universität Münster, Germany; and Institute for Translational Neuroscience, University of Münster, Germany., Pelin H; International Max Planck Research School for Translational Psychiatry, Germany; and Max Planck Institute of Psychiatry, Germany., Streit F; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Germany., Papiol S; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Germany; Department of Psychiatry and Psychotherapy, University Hospital Munich, Germany; and Centro de Investigación Biomedica en Red de Salud Mental (CIBERSAM), Spain., Adams MJ; Division of Psychiatry, University of Edinburgh, UK., Adolfsson R; Department of Clinical Sciences, Medical Faculty, Umeå University, Sweden., Adorjan K; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Germany; and Department of Psychiatry and Psychotherapy, University Hospital Munich, Germany., Agartz I; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Sweden; Department of Psychiatric Research, Diakonhjemmet Hospital, Norway; and NORMENT Centre, Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Norway., Aminoff SR; Division of Mental Health and Addiction, Oslo University Hospital, Norway; and NORMENT Centre, Inst of Clinical Medicine, University of Oslo, Norway., Anderson-Schmidt H; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Germany., Andreassen OA; NORMENT Centre, Inst of Clinical Medicine, University of Oslo, Norway; and Division of Mental Health and Addiction, Oslo University Hosptial, Norway., Ardau R; Unit of Clinical Pharmacology, University Hospital Agency of Cagliari, Italy., Aubry JM; Faculty of medicine, University of Geneva, Switzerland; and Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Germany., Balaban C; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Germany., Bass N; Division of Psychiatry, University College London, UK., Baune BT; Department of Psychiatry, University of Münster, Germany; Department of Psychiatry, Melbourne Medical School, The University of Melbourne, Australia; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Australia; and Discipline of Psychiatry, Adelaide Medical School, The University of Adelaide, Australia., Bellivier F; Universite de Paris, France; INSERM UMRS 1144, France; and DMU Neurosciences, GHU Lariboisière Fernand Widal, Departement de Psychiatrie, APHP, France., Benabarre A; Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Spain., Bengesser S; Department of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, Austria., Berrettini WH; Psychiatry, University of Pennsylvania, USA., Boks MP; Psychiatry, UMC Utrecht Brain Center, the Netherlands., Bromet EJ; Department of Psychiatry, Stony Brook University, USA., Brosch K; Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Germany., Budde M; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Germany., Byerley W; Psychiatry, University of California San Francisco, USA., Cervantes P; Department of Psychiatry, McGill University, Canada., Chillotti C; Unit of Clinical Pharmacology, University Hospital Agency of Cagliari, Italy., Cichon S; Department of Biomedicine, University of Basel, Switzerland; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Germany; Institute of Medical Genetics and Pathology, University Hospital Basel, Switzerland; and Institute of Neuroscience and Medicine (INM-1), Research Centre Julich, Germany., Clark SR; Discipline of Psychiatry, University of Adelaide, Australia; and Bazil Hetzel Institute, Australia., Comes AL; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Germany; Department of Psychiatry and Psychotherapy, University Hospital Munich, Germany; and International Max Planck Research School for Translational Psychiatry, Germany., Corvin A; Department of Psychiatry & Trinity Translational Medicine Institute, Trinity College Dublin, Ireland., Coryell W; University of Iowa Hospitals and Clinics, USA., Craddock N; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, UK., Craig DW; Translational Genomics, USC, USA., Croarkin PE; Department of Psychiatry and Psychology, Mayo Clinic, USA., Cruceanu C; Department of Translational Research, Max Planck Institute of Psychiatry, Germany., Czerski PM; Department of Psychiatric Genetics, Poznan University of Medical Sciences, Poland., Dalkner N; Department of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, Austria., Dannlowski U; Institute for Translational Psychiatry, Westfälische Wilhelms-Universität Münster, Germany., Degenhardt F; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Germany; and Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Germany., Del Zompo M; Department of Biomedical Science, Section of Neuroscience & Clinical Pharmacology, University of Cagliari, Italy; and Unit of Clinical Pharmacology, University Hospital Agency of Cagliari, Italy., DePaulo JR; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, USA., Djurovic S; Department of Medical Genetics, Oslo University Hospital Ullevål, Norway; and NORMENT, Department of Clinical Science, University of Bergen, Norway., Edenberg HJ; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, USA., Eissa MA; Division of Psychiatry, University College London, UK., Elvsåshagen T; NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Norway., Etain B; Universite de Paris, France; INSERM UMRS 1144, France; and DMU Neurosciences, GHU Lariboisière Fernand Widal, Departement de Psychiatrie, APHP, France., Fanous AH; Department of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, USA; and VA NY Harbor Healthcare System, USA., Fellendorf F; Department of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, Austria., Fiorentino A; Division of Psychiatry, University College London, UK., Forstner AJ; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Germany; and Centre for Human Genetics, University of Marburg, Germany., Frye MA; Department of Psychiatry and Psychology, Mayo Clinic, USA., Fullerton JM; Neuroscience Research Australia, Australia; and School of Medical Sciences, University of New South Wales, Australia., Gade K; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Germany., Garnham J; Nova Scotia Health Authority, Canada., Gershon E; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, USA; and Department of Human Genetics, University of Chicago, USA., Gill M; Department of Psychiatry & Trinity Translational Medicine Institute, Trinity College Dublin, Ireland., Goes FS; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, USA., Gordon-Smith K; Psychological Medicine, University of Worcester, UK., Grof P; Mood Disorders Centre of Ottawa, Canada; and Department of Psychiatry, University of Toronto, Canada., Guzman-Parra J; Mental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Spain., Hahn T; Institute for Translational Psychiatry, Westfälische Wilhelms-Universität Münster, Germany., Hasler R; Cell Biology, SUNY Downstate Medical Center College of Medicine, USA; and Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, USA., Heilbronner M; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Germany., Heilbronner U; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Germany., Jamain S; Universite Paris Est Creteil, France; and INSERM U 955, Neuropsychiatrie Translationnelle, France., Jimenez E; Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Spain., Jones I; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, UK., Jones L; Psychological Medicine, University of Worcester, UK., Jonsson L; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Sweden., Kahn RS; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, USA., Kelsoe JR; Department of Psychiatry, University of California San Diego, USA., Kennedy JL; Department of Psychiatry, University of Toronto, Canada; The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Canada; and Institute of Medical Science, University of Toronto, Canada., Kircher T; Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Germany., Kirov G; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, UK., Kittel-Schneider S; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Germany; and Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital Wurzburg, Germany., Klöhn-Saghatolislam F; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Germany., Knowles JA; Cell Biology, SUNY Downstate Medical Center College of Medicine, USA; and Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, USA., Kranz TM; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Germany., Lagerberg TV; NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hosptial, Norway., Landen M; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Sweden; and Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Sweden., Lawson WB; Department of Psychiatry and Behavioral Sciences, Howard University Hospital, USA., Leboyer M; Universite Paris Est Creteil, France; and INSERM U 955, Neuropsychiatrie Translationnelle, France., Li QS; Neuroscience, Janssen Research & Development, USA., Maj M; Department of Psychiatry, University of Campania 'Luigi Vanvitelli', Italy., Malaspina D; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, USA; and Department of Genetics & Genomics, Icahn School of Medicine at Mount Sinai, USA., Manchia M; Unit of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Italy and Department of Pharmacology, Dalhousie University, Canada., Mayoral F; Mental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Spain., McElroy SL; Research Institute, Lindner Center of HOPE, USA., McInnis MG; Department of Psychiatry, University of Michigan, USA., McIntosh AM; Division of Psychiatry, University of Edinburgh, UK., Medeiros H; Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, USA., Melle I; NORMENT Centre, Division of Mental Health and Addiction, Institute of Clinical Medicine and Diakonhjemmet Hospital, University of Oslo, Norway; and Division of Mental Health and Addiction, Oslo University Hospital, Norway., Milanova V; Psychiatric Clinic, Alexander University Hospital, Bulgaria., Mitchell PB; School of Psychiatry, University of New South Wales, Australia., Monteleone P; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Italy., Monteleone AM; Department of Psychiatry, University of Campania 'Luigi Vanvitelli', Italy., Nöthen MM; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Germany., Novak T; National Institute of Mental Health, Czech Republic., Nurnberger JI; Psychiatry, Indiana University School of Medicine, USA., O'Brien N; Division of Psychiatry, University College London, UK., O'Connell KS; Division of Mental Health and Addiction, Oslo University Hospital, Norway; and NORMENT Centre, Inst of Clinical Medicine, University of Oslo, Norway., O'Donovan C; Department of Psychiatry, Dalhousie University, Canada., O'Donovan MC; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, UK., Opel N; Institute for Translational Psychiatry, Westfälische Wilhelms-Universität Münster, Germany., Ortiz A; Department of Psychiatry, University of Toronto, Toronto, Canada; and Centre for Addiction and Mental Health, Toronto, Canada., Owen MJ; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, UK., Pålsson E; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Sweden., Pato C; Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, USA., Pato MT; Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, USA., Pawlak J; Department of Psychiatric Genetics, Poznan University of Medical Sciences, Poland., Pfarr JK; Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Germany., Pisanu C; Department of Biomedical Science, Section of Neuroscience & Clinical Pharmacology, University of Cagliari, Italy., Potash JB; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, USA., Rapaport MH; Department of Psychiatry and Behavioral Sciences, Emory University, USA., Reich-Erkelenz D; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Germany., Reif A; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Germany., Reininghaus E; Department of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, Austria., Repple J; Institute for Translational Psychiatry, Westfälische Wilhelms-Universität Münster, Germany., Richard-Lepouriel H; Department of Psychiatry, Geneva University Hospitals, Switzerland., Rietschel M; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Germany., Ringwald K; Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Germany., Roberts G; School of Psychiatry, University of New South Wales, Australia., Rouleau G; Montreal Neurological Institute, Canada and Department of Neurology, McGill University, Canada., Schaupp S; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Germany., Scheftner WA; Department of Psychiatry, Rush Medical College, USA., Schmitt S; Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Germany., Schofield PR; Neuroscience Research Australia, Australia; and School of Medical Sciences, University of New South Wales, Australia., Schubert KO; Discipline of Psychiatry, University of Adelaide, Australia; and Northern Adelaide Mental Health Service, SA Health, Australia., Schulte EC; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Germany; and Department of Psychiatry and Psychotherapy, University Hospital Munich, Germany., Schweizer B; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, USA., Senner F; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Germany; and Department of Psychiatry and Psychotherapy, University Hospital Munich, Germany., Severino G; Department of Biomedical Science, Section of Neuroscience & Clinical Pharmacology, University of Cagliari, Italy., Sharp S; Division of Psychiatry, University College London, UK., Slaney C; Nova Scotia Health Authority, Canada., Smeland OB; Division of Mental Health and Addiction, Oslo University Hospital, Norway; and NORMENT Centre, Inst of Clinical Medicine, University of Oslo, Norway., Sobell JL; Psychiatry and the Behavioral Sciences, University of Southern California, USA., Squassina A; Department of Psychiatry, Dalhousie University, Canada; and Department of Biomedical Science, Section of Neuroscience & Clinical Pharmacology, University of Cagliari, Italy., Stopkova P; National Institute of Mental Health, Czech Republic., Strauss J; Department of Psychiatry, University of Toronto, Canada; The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Canada; and Institute of Medical Science, University of Toronto, Canada., Tortorella A; Department of Psychiatry, University of Perugia, Italy., Turecki G; Department of Psychiatry, McGill University, Canada; and Douglas Institute, McGill University, Canada., Twarowska-Hauser J; Department of Psychiatric Genetics, Poznan University of Medical Sciences, Poland., Veldic M; Department of Psychiatry and Psychology, Mayo Clinic, USA., Vieta E; Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Spain., Vincent JB; Department of Psychiatry, University of Toronto, Canada; The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Canada; and Institute of Medical Science, University of Toronto, Canada., Xu W; Dalla Lana School of Public Health, Biostatistics Division, University of Toronto, Canada., Zai CC; Department of Psychiatry, University of Toronto, Canada; The Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Canada; Institute of Medical Science, University of Toronto, Canada; Laboratory Medicine and Pathobiology, University of Toronto, Canada; and Harvard T.H. Chan School of Public Health, USA., Zandi PP; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, USA., Di Florio A; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, UK., Smoller JW; Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry and Center for Genomic Medicine, Massachusetts General Hospital, USA; and Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, USA., Biernacka JM; Department of Psychiatry and Psychology, Mayo Clinic, USA; and Department of Health Sciences Research, Mayo Clinic, USA., McMahon FJ; Human Genetics Branch, Intramural Research Program, National Institute of Mental Health, USA., Alda M; National Institute of Mental Health, Czech Republic; and Department of Psychiatry, Dalhousie University, Canada., Müller-Myhsok B; Max Planck Institute of Psychiatry, Germany., Koutsouleris N; Department of Psychiatry and Psychotherapy, University Hospital Munich, Germany; Max Planck Institute of Psychiatry, Germany; and Institute of Psychiatry, Psychology and Neuroscience, Kings College London, UK., Falkai P; Department of Psychiatry and Psychotherapy, University Hospital Munich, Germany., Freimer NB; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, USA; and Human Genetics, University of California Los Angeles, USA., Andlauer TFM; Department of Neurology, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Germany., Schulze TG; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Germany; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Germany; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Germany; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, USA; and Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, USA., Ophoff RA; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, USA; Human Genetics, University of California Los Angeles, USA; and Psychiatry, Erasmus University Medical Center, the Netherlands.
Corporate Authors: Psychiatric Genomics Consortium (PGC) Bipolar Disorder Working Group, International Consortium on Lithium Genetics (ConLiGen), Colombia-US Cross Disorder Collaboration in Psychiatric Genetics
Source: The British journal of psychiatry : the journal of mental science [Br J Psychiatry] 2021 Dec; Vol. 219 (6), pp. 659-669.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cambridge University Press Country of Publication: England NLM ID: 0342367 Publication Model: Print Cited Medium: Internet ISSN: 1472-1465 (Electronic) Linking ISSN: 00071250 NLM ISO Abbreviation: Br J Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1472-1465
DOI:10.1192/bjp.2021.102