Systems analysis of immune responses to attenuated P. falciparum malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity.
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| Title: | Systems analysis of immune responses to attenuated P. falciparum malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity. |
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| Authors: | Du Y; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, United States of America., Hertoghs N; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, United States of America., Duffy FJ; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, United States of America., Carnes J; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, United States of America., McDermott SM; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, United States of America., Neal ML; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, United States of America., Schwedhelm KV; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America., McElrath MJ; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America., De Rosa SC; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America., Aitchison JD; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, United States of America.; Department of Pediatrics, University of Washington, Seattle, Washington, United States of America.; Department of Biochemistry, University of Washington, Seattle, Washington, United States of America., Stuart KD; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, United States of America.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.; Department of Pediatrics, University of Washington, Seattle, Washington, United States of America.; Department of Global Health, University of Washington, Seattle, Washington, United States of America. |
| Source: | PLoS pathogens [PLoS Pathog] 2022 Feb 02; Vol. 18 (2), pp. e1010282. Date of Electronic Publication: 2022 Feb 02 (Print Publication: 2022). |
| Publication Type: | Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1553-7374 |
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| DOI: | 10.1371/journal.ppat.1010282 |
