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ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway.

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Title: ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway.
Authors: Li S; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China., Yang H; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China., Li W; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China., Liu JY; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China., Ren LW; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China., Yang YH; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China., Ge BB; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China., Zhang YZ; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China., Fu WQ; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China., Zheng XJ; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China., Du GH; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China. dugh@imm.ac.cn.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China. dugh@imm.ac.cn., Wang JH; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China. wjh@imm.ac.cn.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China. wjh@imm.ac.cn.
Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2022 Oct; Vol. 43 (10), pp. 2709-2722. Date of Electronic Publication: 2022 Mar 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway.
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  Data: <searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Liu+JY%22">Liu JY</searchLink>; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Ren+LW%22">Ren LW</searchLink>; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Yang+YH%22">Yang YH</searchLink>; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Ge+BB%22">Ge BB</searchLink>; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YZ%22">Zhang YZ</searchLink>; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Fu+WQ%22">Fu WQ</searchLink>; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Zheng+XJ%22">Zheng XJ</searchLink>; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.<br /><searchLink fieldCode="AU" term="%22Du+GH%22">Du GH</searchLink>; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China. dugh@imm.ac.cn.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China. dugh@imm.ac.cn.<br /><searchLink fieldCode="AU" term="%22Wang+JH%22">Wang JH</searchLink>; The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China. wjh@imm.ac.cn.; Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China. wjh@imm.ac.cn.
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  Data: <searchLink fieldCode="JN" term="%22100956087%22">Acta pharmacologica Sinica</searchLink> [Acta Pharmacol Sin] 2022 Oct; Vol. 43 (10), pp. 2709-2722. <i>Date of Electronic Publication: </i>2022 Mar 30.
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1038/s41401-022-00894-7
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      – Code: eng
        Text: English
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        StartPage: 2709
    Titles:
      – TitleFull: ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway.
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            NameFull: Li S
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            – D: 01
              M: 10
              Text: 2022 Oct
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              Y: 2022
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