Inhibition of IRAK4 dysregulates SARS-CoV-2 spike protein-induced macrophage inflammatory and glycolytic reprogramming.
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| Title: | Inhibition of IRAK4 dysregulates SARS-CoV-2 spike protein-induced macrophage inflammatory and glycolytic reprogramming. |
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| Authors: | Umar S; Jesse Brown VA Medical Center, Chicago, IL, USA.; Department of Medicine, Division of Rheumatology, University of Illinois at Chicago, 840 S Wood Street, CSB suite 1114, Chicago, IL, 60612, USA., Palasiewicz K; Jesse Brown VA Medical Center, Chicago, IL, USA.; Department of Medicine, Division of Rheumatology, University of Illinois at Chicago, 840 S Wood Street, CSB suite 1114, Chicago, IL, 60612, USA., Meyer A; Jesse Brown VA Medical Center, Chicago, IL, USA.; Department of Medicine, Division of Rheumatology, University of Illinois at Chicago, 840 S Wood Street, CSB suite 1114, Chicago, IL, 60612, USA., Kumar P; Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, IL, USA., Prabhakar BS; Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, IL, USA., Volin MV; Department of Microbiology and Immunology, Midwestern University, Downers Grove, IL, USA., Rahat R; Department of Medicine, Division of Rheumatology, University of Illinois at Chicago, 840 S Wood Street, CSB suite 1114, Chicago, IL, 60612, USA., Al-Awqati M; Jesse Brown VA Medical Center, Chicago, IL, USA.; Department of Medicine, Division of Rheumatology, University of Illinois at Chicago, 840 S Wood Street, CSB suite 1114, Chicago, IL, 60612, USA., Chang HJ; Jesse Brown VA Medical Center, Chicago, IL, USA.; Department of Medicine, Division of Rheumatology, University of Illinois at Chicago, 840 S Wood Street, CSB suite 1114, Chicago, IL, 60612, USA., Zomorrodi RK; Department of Medicine, Division of Rheumatology, University of Illinois at Chicago, 840 S Wood Street, CSB suite 1114, Chicago, IL, 60612, USA., Rehman J; Department of Pharmacology and Regenerative Medicine, The University of Illinois at Chicago, Chicago, IL, USA.; Department of Medicine, Division of Cardiology, University of Illinois at Chicago, Chicago, IL, USA., Shahrara S; Jesse Brown VA Medical Center, Chicago, IL, USA. shahrara@uic.edu.; Department of Medicine, Division of Rheumatology, University of Illinois at Chicago, 840 S Wood Street, CSB suite 1114, Chicago, IL, 60612, USA. shahrara@uic.edu. |
| Source: | Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2022 May 19; Vol. 79 (6), pp. 301. Date of Electronic Publication: 2022 May 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1420-9071 |
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| DOI: | 10.1007/s00018-022-04329-8 |
