Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation.
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| Title: | Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation. |
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| Authors: | Bufton JC; School of Biochemistry, University of Bristol; University Walk, Bristol BS8 1TD, UK., Powers KT; School of Biochemistry, University of Bristol; University Walk, Bristol BS8 1TD, UK., Szeto JA; School of Biochemistry, University of Bristol; University Walk, Bristol BS8 1TD, UK., Toelzer C; School of Biochemistry, University of Bristol; University Walk, Bristol BS8 1TD, UK., Berger I; School of Biochemistry, University of Bristol; University Walk, Bristol BS8 1TD, UK.; Max Planck Bristol Centre for Minimal Biology, Cantock's Close, Bristol BS8 1TS, UK., Schaffitzel C; School of Biochemistry, University of Bristol; University Walk, Bristol BS8 1TD, UK. |
| Source: | Nucleic acids research [Nucleic Acids Res] 2022 Jun 10; Vol. 50 (10), pp. 5934-5947. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1362-4962 |
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| DOI: | 10.1093/nar/gkac421 |
