Rapid, scalable assessment of SARS-CoV-2 cellular immunity by whole-blood PCR.

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Title: Rapid, scalable assessment of SARS-CoV-2 cellular immunity by whole-blood PCR.
Authors: Schwarz M; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Therapeutics Discovery, Department of Oncological Sciences and Pharmacological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Torre D; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Therapeutics Discovery, Department of Oncological Sciences and Pharmacological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lozano-Ojalvo D; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Tan AT; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Tabaglio T; Institute of Molecular and Cell Biology, IMCB, A*STAR, Singapore, Singapore., Mzoughi S; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Therapeutics Discovery, Department of Oncological Sciences and Pharmacological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sanchez-Tarjuelo R; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; National Center for Microbiology, Carlos III Health Institute, Madrid, Spain., Le Bert N; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Lim JME; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Hatem S; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Tuballes K; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Camara C; Department of Immunology, University Hospital La Paz-IdiPAZ, Madrid, Spain., Lopez-Granados E; Department of Immunology, University Hospital La Paz-IdiPAZ, Madrid, Spain., Paz-Artal E; Department of Immunology, Research Institution, Sanitaria Hospital, Madrid, Spain.; Department of Immunology, Ophthalmology and ENT, Complutense University of Madrid, Madrid, Spain.; CIBER de Enfermedades Infecciosas (CIBERINFEC), Carlos III Health Institute, Madrid, Spain., Correa-Rocha R; Laboratory of Immune-Regulation, Research Institute Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain., Ortiz A; Department of Nephrology, IIS-Fundación Jimenez Díaz, Madrid, Spain., Lopez-Hoyos M; Department of Immunology, Hospital University of Marqués de Valdecilla-IDIVAL, Santander, Spain., Portoles J; Department of Nephrology, Hospital of Puerta de Hierro, Madrid, Spain., Cervera I; National Center for Microbiology, Carlos III Health Institute, Madrid, Spain., Gonzalez-Perez M; National Center for Microbiology, Carlos III Health Institute, Madrid, Spain., Bodega-Mayor I; National Center for Microbiology, Carlos III Health Institute, Madrid, Spain., Conde P; National Center for Microbiology, Carlos III Health Institute, Madrid, Spain., Oteo-Iglesias J; National Center for Microbiology, Carlos III Health Institute, Madrid, Spain.; CIBER de Enfermedades Infecciosas (CIBERINFEC), Carlos III Health Institute, Madrid, Spain., Borobia AM; Clinical Pharmacology, University Hospital La Paz-IDIPAZ, Platform of Clinical Research Units and Clinical Trials, Spain Faculty of Medicine Autonomous University of Madrid, Madrid, Spain., Carcas AJ; Clinical Pharmacology, University Hospital La Paz-IDIPAZ, Platform of Clinical Research Units and Clinical Trials, Spain Faculty of Medicine Autonomous University of Madrid, Madrid, Spain., Frías J; Clinical Pharmacology, University Hospital La Paz-IDIPAZ, Platform of Clinical Research Units and Clinical Trials, Spain Faculty of Medicine Autonomous University of Madrid, Madrid, Spain., Belda-Iniesta C; Carlos III Health Institute, Madrid, Spain., Ho JSY; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Nunez K; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Therapeutics Discovery, Department of Oncological Sciences and Pharmacological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hekmaty S; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Mohammed K; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Marsiglia WM; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Carreño JM; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Dar AC; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Therapeutics Discovery, Department of Oncological Sciences and Pharmacological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Berin C; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Nicoletti G; Hyris Limited, London, UK., Della Noce I; Hyris Limited, London, UK., Colombo L; Hyris Limited, London, UK., Lapucci C; Genetic Unit, Synlab Italia, Castenedolo, Italy., Santoro G; Genetic Unit, Synlab Italia, Castenedolo, Italy., Ferrari M; IRCCS, SDN, Napoli, Italy., Nie K; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Human Immune Monitoring Core, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Patel M; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Human Immune Monitoring Core, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Barcessat V; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Gnjatic S; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Human Immune Monitoring Core, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Harris J; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Human Immune Monitoring Core, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sebra R; Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Sema4, a Mount Sinai venture, Stamford, CT, USA.; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Merad M; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Human Immune Monitoring Core, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kim-Schulze S; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Human Immune Monitoring Core, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Marazzi I; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bertoletti A; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore. antonio@duke-nus.edu.sg., Ochando J; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. jordi.ochando@mssm.edu.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. jordi.ochando@mssm.edu.; National Center for Microbiology, Carlos III Health Institute, Madrid, Spain. jordi.ochando@mssm.edu., Guccione E; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ernesto.guccione@mssm.edu.; Center for Therapeutics Discovery, Department of Oncological Sciences and Pharmacological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ernesto.guccione@mssm.edu.; Bioinformatics for Next Generation Sequencing (BiNGS) Shared Resource Facility, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ernesto.guccione@mssm.edu.
Source: Nature biotechnology [Nat Biotechnol] 2022 Nov; Vol. 40 (11), pp. 1680-1689. Date of Electronic Publication: 2022 Jun 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1546-1696
DOI:10.1038/s41587-022-01347-6