In-Depth Characterization of a Re-Engineered Cholera Toxin Manufacturing Process Using Growth-Decoupled Production in Escherichia coli.

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Title: In-Depth Characterization of a Re-Engineered Cholera Toxin Manufacturing Process Using Growth-Decoupled Production in Escherichia coli.
Authors: Danielewicz N; enGenes Biotech GmbH, Mooslackengasse 17, 1190 Vienna, Austria.; Department of Biotechnology, University of Natural Resources and Life Sciences, Muthgasse 11, 1190 Vienna, Austria., Dai W; School of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK., Rosato F; Faculty of Biology, University of Freiburg, Schänzlestraße 1, 79104 Freiburg, Germany.; Signaling Research Centers BIOSS and CIBSS, University of Freiburg, Schänzlestraße 18, 79104 Freiburg, Germany., Webb ME; School of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK., Striedner G; Department of Biotechnology, University of Natural Resources and Life Sciences, Muthgasse 11, 1190 Vienna, Austria., Römer W; Faculty of Biology, University of Freiburg, Schänzlestraße 1, 79104 Freiburg, Germany.; Signaling Research Centers BIOSS and CIBSS, University of Freiburg, Schänzlestraße 18, 79104 Freiburg, Germany.; Freiburg Institute for Advanced Studies (FRIAS), University of Freiburg, 79104 Freiburg, Germany., Turnbull WB; School of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK., Mairhofer J; enGenes Biotech GmbH, Mooslackengasse 17, 1190 Vienna, Austria.
Source: Toxins [Toxins (Basel)] 2022 Jun 08; Vol. 14 (6). Date of Electronic Publication: 2022 Jun 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651 (Electronic) Linking ISSN: 20726651 NLM ISO Abbreviation: Toxins (Basel) Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2072-6651
DOI:10.3390/toxins14060396