Changes in laboratory value improvement and mortality rates over the course of the pandemic: an international retrospective cohort study of hospitalised patients infected with SARS-CoV-2.

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Title: Changes in laboratory value improvement and mortality rates over the course of the pandemic: an international retrospective cohort study of hospitalised patients infected with SARS-CoV-2.
Authors: Hong C; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Zhang HG; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., L'Yi S; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Weber G; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Avillach P; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Tan BWQ; Department of Medicine, National University Hospital, Singapore., Gutiérrez-Sacristán A; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Bonzel CL; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Palmer NP; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Malovini A; Laboratory of Informatics and Systems Engineering for Clinical Research, Istituti Clinici Scientifici Maugeri SpA SB IRCCS, Pavia, Lombardia, Italy., Tibollo V; Laboratory of Informatics and Systems Engineering for Clinical Research, Istituti Clinici Scientifici Maugeri SpA SB IRCCS, Pavia, Lombardia, Italy., Luo Y; Department of Preventive Medicine, Northwestern University, Evanston, Illinois, USA., Hutch MR; Department of Preventive Medicine, Northwestern University, Evanston, Illinois, USA., Liu M; Department of Biostatistics, Harvard University T H Chan School of Public Health, Boston, Massachusetts, USA., Bourgeois F; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Bellazzi R; Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy., Chiovato L; Unit of Internal Medicine and Endocrinology, Istituti Clinici Scientifici Maugeri SpA SB IRCCS, Pavia, Lombardia, Italy., Sanz Vidorreta FJ; Department of Medicine, David Geffen School of Medicine, Los Angeles, California, USA., Le TT; Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Wang X; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Yuan W; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Neuraz A; Department of Biomedical Informatics, Hopital Universitaire Necker-Enfants Malades, Paris, Île-de-France, France., Benoit V; IT department, Innovation & Data, APHP Greater Paris University Hospital, Paris, France., Moal B; IAM unit, Bordeaux University Hospital, Bordeaux, France., Morris M; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Hanauer DA; Department of Learning Health Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA., Maidlow S; MICHR Informatics, University of Michigan, Ann Arbor, Michigan, USA., Wagholikar K; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Murphy S; Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA., Estiri H; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Makoudjou A; Institute of Medical Biometry and Statistics, University of Freiburg Faculty of Medicine, Freiburg, Baden-Württemberg, Germany., Tippmann P; Institute of Medical Biometry and Statistics, Medical Center-University of Freiburg, Freiburg, Baden-Württemberg, Germany., Klann J; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Follett RW; Department of Medicine, David Geffen School of Medicine, Los Angeles, California, USA., Gehlenborg N; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Omenn GS; Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA., Xia Z; Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Dagliati A; Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy., Visweswaran S; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Kansas, USA., Patel LP; Department of Internal Medicine, Division of Medical Informatics, University of Kansas Medical Center, Kansas City, Kansas, USA., Mowery DL; Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Schriver ER; Data Analytics Center, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA., Samayamuthu MJ; Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Kavuluru R; Institute for Biomedical Informatics, University of Kentucky, Lexington, Kentucky, USA., Lozano-Zahonero S; Institute of Medical Biometry and Statistics, University of Freiburg Faculty of Medicine, Freiburg, Baden-Württemberg, Germany., Zöller D; Institute of Medical Biometry and Statistics, University of Freiburg Faculty of Medicine, Freiburg, Baden-Württemberg, Germany., Tan ALM; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Tan BWL; Department of Medicine, National University Hospital, Singapore., Ngiam KY; Department of Surgery, National University Hospital, Singapore., Holmes JH; Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.; Institute for Biomedical Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Schubert P; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, Massachusetts, USA., Cho K; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, Massachusetts, USA., Ho YL; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, Massachusetts, USA., Beaulieu-Jones BK; Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Pedrera-Jiménez M; Health Informatics, Hospital Universitario 12 de Octubre, Madrid, Comunidad de Madrid, Spain., García-Barrio N; Health Informatics, Hospital Universitario 12 de Octubre, Madrid, Comunidad de Madrid, Spain., Serrano-Balazote P; Health Informatics, Hospital Universitario 12 de Octubre, Madrid, Comunidad de Madrid, Spain., Kohane I; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., South A; Department of Pediatrics, Section of Nephrology, Wake Forest University, Winston Salem, North Carolina, USA., Brat GA; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA., Cai T; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA tcai@hsph.harvard.edu.
Corporate Authors: Consortium for Clinical Characterization of COVID-19 by EHR (4CE)
Source: BMJ open [BMJ Open] 2022 Jun 23; Vol. 12 (6), pp. e057725. Date of Electronic Publication: 2022 Jun 23.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-6055
DOI:10.1136/bmjopen-2021-057725