Regulation of age-associated insulin resistance by MT1-MMP-mediated cleavage of insulin receptor.

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Title: Regulation of age-associated insulin resistance by MT1-MMP-mediated cleavage of insulin receptor.
Authors: Guo X; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China., Asthana P; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China., Gurung S; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China., Zhang S; School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China., Wong SKK; School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China., Fallah S; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China., Chow CFW; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.; Centre for Systems Biology Dresden, Max Planck Institute for Molecular Cell and Biology, Dresden, Germany., Che S; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China., Zhai L; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China., Wang Z; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Ge X; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Jiang Z; School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China., Wu J; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China., Zhang Y; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China., Wu X; Respiratory Department, Jinhua Guangfu hospital, Jinhua, China., Xu K; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China., Lin CY; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.; Centre for Chinese Herbal Medicine Drug Development Limited, Hong Kong Baptist University, Hong Kong SAR, China., Kwan HY; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China., Lyu A; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China., Zhou Z; School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China., Bian ZX; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. bzxiang@hkbu.edu.hk.; Centre for Chinese Herbal Medicine Drug Development Limited, Hong Kong Baptist University, Hong Kong SAR, China. bzxiang@hkbu.edu.hk., Wong HLX; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. xavierwong@hkbu.edu.hk.
Source: Nature communications [Nat Commun] 2022 Jun 29; Vol. 13 (1), pp. 3749. Date of Electronic Publication: 2022 Jun 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-022-31563-2