Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells.

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Title: Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells.
Authors: Igarashi N; Project for Cellular Senescence, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.; Department of Maxillofacial Orthognathics, Tokyo Medical and Dental University, Tokyo, Japan., Miyata K; Project for Cellular Senescence, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.; Cancer Cell Communication Project, NEXT-Ganken Program, Japanese Foundation for Cancer Research, Tokyo, Japan., Loo TM; Project for Cellular Senescence, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan., Chiba M; Project for Cellular Senescence, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan., Hanyu A; Project for Cellular Senescence, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan., Nishio M; Project for Cellular Senescence, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan., Kawasaki H; Project for Cellular Senescence, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan., Zheng H; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya, Japan., Toyokuni S; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya, Japan., Kon S; Division of Development and Aging, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan., Moriyama K; Department of Maxillofacial Orthognathics, Tokyo Medical and Dental University, Tokyo, Japan., Fujita Y; Department of Molecular Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Takahashi A; Project for Cellular Senescence, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan. akiko.takahashi@jfcr.or.jp.; Cancer Cell Communication Project, NEXT-Ganken Program, Japanese Foundation for Cancer Research, Tokyo, Japan. akiko.takahashi@jfcr.or.jp.; Advanced Research & Development Programs for Medical Innovation (PRIME), Japan Agency for Medical Research and Development (AMED), Tokyo, Japan. akiko.takahashi@jfcr.or.jp.
Source: Nature communications [Nat Commun] 2022 Jul 18; Vol. 13 (1), pp. 4157. Date of Electronic Publication: 2022 Jul 18.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-022-31642-4