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Heterozygous expression of the Alzheimer's disease-protective PLCγ2 P522R variant enhances Aβ clearance while preserving synapses.

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Title: Heterozygous expression of the Alzheimer's disease-protective PLCγ2 P522R variant enhances Aβ clearance while preserving synapses.
Authors: Solomon S; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. shiden.solomon@kcl.ac.uk.; UK Dementia Research Institute, King's College London, London, UK. shiden.solomon@kcl.ac.uk., Sampathkumar NK; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; UK Dementia Research Institute, King's College London, London, UK.; Alzheimer's Research UK Oxford Drug Discovery Institute, Centre for Medicines Discovery, University of Oxford, Oxford, UK., Carre I; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; UK Dementia Research Institute, King's College London, London, UK., Mondal M; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; UK Dementia Research Institute, King's College London, London, UK., Chennell G; Wohl Cellular Imaging Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Vernon AC; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK., Ruepp MD; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; UK Dementia Research Institute, King's College London, London, UK., Mitchell JC; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. jacqueline.mitchell@kcl.ac.uk.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2022 Jul 27; Vol. 79 (8), pp. 453. Date of Electronic Publication: 2022 Jul 27.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Heterozygous expression of the Alzheimer's disease-protective PLCγ2 P522R variant enhances Aβ clearance while preserving synapses.
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  Data: <searchLink fieldCode="AU" term="%22Solomon+S%22">Solomon S</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. shiden.solomon@kcl.ac.uk.; UK Dementia Research Institute, King's College London, London, UK. shiden.solomon@kcl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Sampathkumar+NK%22">Sampathkumar NK</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; UK Dementia Research Institute, King's College London, London, UK.; Alzheimer's Research UK Oxford Drug Discovery Institute, Centre for Medicines Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Carre+I%22">Carre I</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; UK Dementia Research Institute, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Mondal+M%22">Mondal M</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; UK Dementia Research Institute, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Chennell+G%22">Chennell G</searchLink>; Wohl Cellular Imaging Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Vernon+AC%22">Vernon AC</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ruepp+MD%22">Ruepp MD</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; UK Dementia Research Institute, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Mitchell+JC%22">Mitchell JC</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. jacqueline.mitchell@kcl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%229705402%22">Cellular and molecular life sciences : CMLS</searchLink> [Cell Mol Life Sci] 2022 Jul 27; Vol. 79 (8), pp. 453. <i>Date of Electronic Publication: </i>2022 Jul 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9705402 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1420-9071 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221420682X%22">1420682X </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Life Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00018-022-04473-1
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              Text: 2022 Jul 27
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